C
Chung-Nga Ko
Researcher at Hong Kong Baptist University
Publications - 19
Citations - 859
Chung-Nga Ko is an academic researcher from Hong Kong Baptist University. The author has contributed to research in topics: Cell cycle checkpoint & Adduct. The author has an hindex of 11, co-authored 19 publications receiving 593 citations.
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Journal ArticleDOI
Development of a Long-Lived Luminescence Probe for Visualizing β-Galactosidase in Ovarian Carcinoma Cells.
Wanhe Wang,Kasipandi Vellaisamy,Guodong Li,Chun Wu,Chung-Nga Ko,Chung-Hang Leung,Dik-Lung Ma +6 more
TL;DR: A novel iridium(III)-based probe 1 is designed and synthesized for discriminating ovarian carcinoma cell lines from normal cell lines and could be potentially used as a useful probe for detecting β-gal expression in the context of ovarian cancer diagnostics.
Journal ArticleDOI
Cell imaging of dopamine receptor using agonist labeling iridium(iii) complex.
Kasipandi Vellaisamy,Guodong Li,Chung-Nga Ko,Hai-Jing Zhong,Sarwat Fatima,Hiu Yee Kwan,Chun-Yuen Wong,Wai-Jing Kwong,Weihong Tan,Weihong Tan,Chung-Hang Leung,Dik-Lung Ma +11 more
TL;DR: A long-lived complex 13 could selectively bind to dopamine receptors (D1R/D2R) and monitor their internalization in living cells.
Journal ArticleDOI
A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe
Zhen-Zhen Dong,Lihua Lu,Lihua Lu,Chung-Nga Ko,Chao Yang,Shengnan Li,Ming-Yuen Lee,Chung-Hang Leung,Dik-Lung Ma +8 more
TL;DR: Practical application of the detection platform for visualizing the intracellular GSH distribution in living zebrafish has been demonstrated and the luminescence intensity responded linearly with the GSH concentration.
Journal ArticleDOI
Dual function luminescent transition metal complexes for cancer theranostics: The combination of diagnosis and therapy
TL;DR: Optical imaging possesses a number of notable advantages that renders it as an attractive diagnostic modality, and transition metal complexes have attracted recent attention as alternatives to conventional dyes due to their advantages of large Stokes shifts, long lifetimes, and ease of structural modifications.
Journal ArticleDOI
A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish
Jin-Biao Liu,Jin-Biao Liu,Chao Yang,Chung-Nga Ko,Kasipandi Vellaisamy,Binrui Yang,Ming-Yuen Lee,Chung-Hang Leung,Dik-Lung Ma +8 more
TL;DR: In this article, a long-lived iridium(III) complex probe Ir_1 for bisulfite detection has been synthesized, containing double aldehyde groups in the N^N donor ligand.