G
Guofeng Qian
Researcher at Zhejiang University
Publications - 23
Citations - 927
Guofeng Qian is an academic researcher from Zhejiang University. The author has contributed to research in topics: Cell cycle & Cell cycle checkpoint. The author has an hindex of 15, co-authored 19 publications receiving 704 citations.
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Journal ArticleDOI
Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway.
Gang Wang,Rui Cao,Yongzhi Wang,Guofeng Qian,Han C. Dan,Wei Jiang,Lingao Ju,Min Wu,Yu Xiao,Xinghuan Wang +9 more
TL;DR: This study for the first time revealed that simvastatin inhibited bladder cancer cell proliferation and induced cell cycle arrest at G1/G0 phase via PPARγ signalling pathway.
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Co-expression network analysis identified FCER1G in association with progression and prognosis in human clear cell renal cell carcinoma.
Liang Chen,Lushun Yuan,Yongzhi Wang,Gang Wang,Yuan Zhu,Rui Cao,Guofeng Qian,Conghua Xie,Xuefeng Liu,Yu Xiao,Xinghuan Wang +10 more
TL;DR: Using weighted gene co-expression analysis, FCER1G was identified and validated in association with ccRCC progression and prognosis, which might improve the prognosis by influencing immune-related pathways.
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Co-expression network analysis identified six hub genes in association with progression and prognosis in human clear cell renal cell carcinoma (ccRCC)
TL;DR: Six hub genes were identified to be associated with progression and prognosis of ccRCC, and they might lead to poor prognosis by regulating p53 signaling pathway.
Journal ArticleDOI
Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis
Lushun Yuan,Bo Shu,Bo Shu,Liang Chen,Kaiyu Qian,Yongzhi Wang,Guofeng Qian,Yuan Zhu,Xinyue Cao,Conghua Xie,Yu Xiao,Xinghuan Wang +11 more
TL;DR: Based on the co-expression analysis, COL3A1 was identified in the association with progression and prognosis of BCa, which might refer a poor prognosisprobably by regulating MAPK signaling pathway.
Journal ArticleDOI
Identification of Biomarkers Associated With Pathological Stage and Prognosis of Clear Cell Renal Cell Carcinoma by Co-expression Network Analysis.
Liang Chen,Lushun Yuan,Kaiyu Qian,Guofeng Qian,Yuan Zhu,Chin-Lee Wu,Han C. Dan,Yu Xiao,Xinghuan Wang +8 more
TL;DR: 29 molecular markers correlated with different pathological stages of clear cell renal cell carcinoma may have important clinical implications for improving risk stratification, therapeutic decision and prognosis prediction in ccRCC patients.