K
Kaiyu Qian
Researcher at Wuhan University
Publications - 52
Citations - 777
Kaiyu Qian is an academic researcher from Wuhan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 13, co-authored 35 publications receiving 452 citations.
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Journal ArticleDOI
Co-expression network analysis identified six hub genes in association with progression and prognosis in human clear cell renal cell carcinoma (ccRCC)
TL;DR: Six hub genes were identified to be associated with progression and prognosis of ccRCC, and they might lead to poor prognosis by regulating p53 signaling pathway.
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Fatty acid oxidation inhibitor etomoxir suppresses tumor progression and induces cell cycle arrest via PPARγ-mediated pathway in bladder cancer.
Songtao Cheng,Gang Wang,Yejinpeng Wang,Liwei Cai,Kaiyu Qian,Lingao Ju,Xuefeng Liu,Yu Xiao,Xinghuan Wang +8 more
TL;DR: Results suggest that by inhibition of FAO with etomoxir may provide a novel avenue to investigate new therapeutic approaches to human bladder cancer (BCa), and suggest the cell cycle arrest could be reversed by PPARγ antagonist GW9662.
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Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis
Lushun Yuan,Bo Shu,Bo Shu,Liang Chen,Kaiyu Qian,Yongzhi Wang,Guofeng Qian,Yuan Zhu,Xinyue Cao,Conghua Xie,Yu Xiao,Xinghuan Wang +11 more
TL;DR: Based on the co-expression analysis, COL3A1 was identified in the association with progression and prognosis of BCa, which might refer a poor prognosisprobably by regulating MAPK signaling pathway.
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Identification of Biomarkers Associated With Pathological Stage and Prognosis of Clear Cell Renal Cell Carcinoma by Co-expression Network Analysis.
Liang Chen,Lushun Yuan,Kaiyu Qian,Guofeng Qian,Yuan Zhu,Chin-Lee Wu,Han C. Dan,Yu Xiao,Xinghuan Wang +8 more
TL;DR: 29 molecular markers correlated with different pathological stages of clear cell renal cell carcinoma may have important clinical implications for improving risk stratification, therapeutic decision and prognosis prediction in ccRCC patients.
Journal ArticleDOI
TM4SF1 regulates apoptosis, cell cycle and ROS metabolism via the PPARγ-SIRT1 feedback loop in human bladder cancer cells.
Rui Cao,Gang Wang,Kaiyu Qian,Liang Chen,Lingao Ju,Guofeng Qian,Chin-Lee Wu,Han C. Dan,Wei Jiang,Min Wu,Yu Xiao,Xinghuan Wang +11 more
TL;DR: It is shown that TM4SF1 is strongly upregulated in human muscle invasive bladder cancer (MIBC) tissues, corroborating the bioinformatical results of transcriptome analysis and suggesting that high expression of TM4 SF1 predicts poor prognosis of MIBC.