G
Guy Serre
Researcher at University of Toulouse
Publications - 167
Citations - 8446
Guy Serre is an academic researcher from University of Toulouse. The author has contributed to research in topics: Filaggrin & Corneodesmosin. The author has an hindex of 53, co-authored 161 publications receiving 7752 citations. Previous affiliations of Guy Serre include Paul Sabatier University & Centre national de la recherche scientifique.
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Journal ArticleDOI
Peptidyl arginine deiminase type 2 (PAD‐2) and PAD‐4 but not PAD‐1, PAD‐3, and PAD‐6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation
Céline Foulquier,Mireille Sebbag,Cyril Clavel,Sabine Chapuy-Regaud,Roula Al Badine,Marie-Claire Méchin,Christian Vincent,Rachida Nachat,Michiyuki Yamada,Hidenari Takahara,Michel Simon,Marina Guerrin,Guy Serre +12 more
TL;DR: PAD-2 and PAD-4 are the only PAD isotypes expressed in the synovial tissue of patients with RA and those with other arthritides, and both enzymes were demonstrable within or in the vicinity of citrullinated fibrin deposits.
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The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies.
Mireille Sebbag,Michel Simon,Christian Vincent,C Masson-Bessière,E Girbal,Jean-Jacques Durieux,Guy Serre +6 more
TL;DR: Results indicate that AKA and APF are largely the same autoantibodies that recognize human epidermal filaggrin and (pro) filag Grin-related proteins of buccal epithelial cells.
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Rheumatoid factor and anticitrullinated protein antibodies in rheumatoid arthritis: diagnostic value, associations with radiological progression rate, and extra-articular manifestations
L De Rycke,I Peene,Ilse Hoffman,Elli Kruithof,Ann Union,Lydie Meheus,K. Lebeer,Bart Wyns,Christian Vincent,Herman Mielants,Luc Boullart,Guy Serre,E M Veys,F De Keyser +13 more
TL;DR: The presence of RA associated antibodies and the SE are indicative for poorer radiological outcome, and presence of extra-articular manifestations is associated with RF but not with anticitrullinated protein antibodies.
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The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis.
Michel Simon,E Girbal,Mireille Sebbag,V Gomès-Daudrix,Christian Vincent,Gilles Salama,Guy Serre +6 more
TL;DR: The identification of filaggrin as a RA-specific autoantigen could contribute to the understanding of the pathogenesis of this disease and, ultimately, to the development of methods for preventing the autoimmune response.
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Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.
Hüseyin Uysal,Robert Bockermann,Kutty Selva Nandakumar,Kutty Selva Nandakumar,Bettina Sehnert,Estelle Bajtner,Åke Engström,Guy Serre,Harald Burkhardt,Marjolein M. G. M. Thunnissen,Rikard Holmdahl,Rikard Holmdahl +11 more
TL;DR: It is proposed that autoimmunity to CII, leading to the production of antibodies specific for both native and citrullinated CII is an important pathogenic factor in the development of RA.