H
H. J. Deeg
Researcher at Fred Hutchinson Cancer Research Center
Publications - 135
Citations - 10921
H. J. Deeg is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Transplantation & Total body irradiation. The author has an hindex of 46, co-authored 135 publications receiving 10718 citations.
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Journal ArticleDOI
Pregnancies following high-dose cyclophosphamide with or without high- dose busulfan or total-body irradiation and bone marrow transplantation
Jean E. Sanders,J Hawley,Wayne C. Levy,Ted Gooley,Buckner Cd,H. J. Deeg,Kristine Doney,Rainer Storb,Keith M. Sullivan,Robert P. Witherspoon,Frederick R. Appelbaum +10 more
TL;DR: Pregnancies among all women who received a marrow transplant are likely to be accompanied by preterm labor and delivery of LBW or VLBW babies who do not seem to be at an increased risk of congenital anomalies, but determination of possible adverse effects of parental exposure to high-dose alkylating agents with or without TBI on children born posttransplant requires longer, additional follow-up.
Journal ArticleDOI
Effects of In Vitro Depletion of T Cells in HLA-Identical Allogeneic Marrow Grafts
Paul J. Martin,J.A. Hansen,C. D. Buckner,Jean E. Sanders,H. J. Deeg,Patricia S. Stewart,FR Appelbaum,Reginald A. Clift,A Fefer,Robert P. Witherspoon +9 more
TL;DR: Optimal application of in vitro manipulation of donor marrow as a method for preventing graft-versus-host disease will require more effective immunosuppression of the recipient in order to assure sustained engraftment and function of donor stem cells.
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Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial.
Rainer Storb,H. J. Deeg,Margaret S. Pepe,FR Appelbaum,Claudio Anasetti,Patrick G. Beatty,William I. Bensinger,Berenson Rj,Buckner Cd,Reginald A. Clift +9 more
TL;DR: Methotrexate/cyclosporine significantly reduced the incidence and severity of acute GVHD, and improved early survival, and did not interfere with sustained hematopoietic engraftment.
Journal ArticleDOI
Secondary cancers after bone marrow transplantation for leukemia or aplastic anemia.
Robert P. Witherspoon,LD Fisher,Gary Schoch,P.J. Martin,Keith M. Sullivan,Jean E. Sanders,H. J. Deeg,Kristine Doney,D Thomas,Rainer Storb +9 more
TL;DR: It is concluded that recipients of bone marrow transplantation have a low but significant risk of a secondary cancer, particularly non-Hodgkin's lymphoma.