H. J. Rahmsdorf

TL;DR: It is shown here by point mutations in the DNA binding domain and by the choice of steroid ligands that repression of AP‐1 activity and transactivation functions of the glucocorticoid receptor (GR) are separable entities.

TL;DR: It is found that UVC‐induced transcriptional activation depends also on the CRE at position −60 of the c‐fos promoter and on the functionality of a CREB, which represents an as yet unrecognized route of U VC‐induced signal transduction, independent of suramin‐inhibitable growth factor receptors and different from the Erk 1,2–p62TCF pathway.

TL;DR: After bacteriophage T7 infection, a protein kinase (EC 27137; ATP:protein phosphotransferase) activity can be demonstrated in E coli in vivo by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and autoradiography Cell-free extracts catalyzed the transfer of the terminal phosphoryl group of [(gamma)-(32)P]ATP to endogenous protein acceptor or to added histone as discussed by the authors.

TL;DR: After infection with bacteriophage T7 the beta' and to a lesser extent the beta subunits of E. coli DNA-dependent RNA polymerase (nucleosidetriphosphate:RNA nucleotidyltransferase) are phosphorylated by a phage-gene-encoded protein kinase (ATP:protein phosphotransferase), probably the molecular basis of the early transcriptional control.

TL;DR: Two transcriptional control mechanisms of T7 can be distinguished both affecting the transcription by E. coli RNA polymerase: An early control and an “early-late” control, both of which appear at approximately the same time.