H
H M Bedford
Researcher at North York General Hospital
Publications - 3
Citations - 308
H M Bedford is an academic researcher from North York General Hospital. The author has contributed to research in topics: Placental growth factor & Preeclampsia. The author has an hindex of 1, co-authored 1 publications receiving 256 citations.
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Utility of whole-exome sequencing for those near the end of the diagnostic odyssey: time to address gaps in care.
Sara L. Sawyer,Taila Hartley,David A. Dyment,Chandree L. Beaulieu,Jeremy Schwartzentruber,Amanda C. Smith,H M Bedford,Geneviève Bernard,Francois P. Bernier,Bernard Brais,Dennis E. Bulman,J. Warman Chardon,David Chitayat,Johnny Deladoëy,Bridget A. Fernandez,Patrick Frosk,Michael T. Geraghty,Brenda Gerull,William T. Gibson,Robert M. Gow,Gail E. Graham,Jane Green,Elise Héon,Gabriella Horvath,A.M. Innes,Nada Jabado,Raymond H. Kim,Robert K. Koenekoop,Aneal Khan,Ordan J. Lehmann,Roberto Mendoza-Londono,Jacques L. Michaud,Sarah M. Nikkel,L S Penney,Constantin Polychronakos,Julie Richer,Guy A. Rouleau,Mark E. Samuels,Victoria Mok Siu,Oksana Suchowersky,Mark A. Tarnopolsky,Grace Yoon,Farah R. Zahir,Jacek Majewski,Kym M. Boycott +44 more
TL;DR: The analysis of this dataset showed that these known disease genes were not identified prior to WES enrollment for two key reasons: genetic heterogeneity associated with a clinical diagnosis and atypical presentation of known, clinically recognized diseases.
Journal ArticleDOI
Prenatal screening for preeclampsia: the roles of PlGF and PAPP-A in the first trimester and PlGF and SFlt-1/PlGF ratio in the early second trimester
Tianhua Huang,Shamim Rashid,Megan Priston,E. Rasasakaram,Ellen Mak-Tam,Clare A. Gibbons,Elad Mei-Dan,H M Bedford +7 more
TL;DR: In this paper , a case-control study using frozen residual blood samples from women who had aneuploidy screening and delivered at a tertiary center was used to assess the accuracy of (1) a combination of maternal characteristics, maternal serum pregnancy-associated plasma protein A, and placental growth factor in the screening for preeclampsia in the first trimester; and (2) placenta growth factor or soluble fms-like tyrosine kinase-1-placental growth ratio in the early second trimester.
Journal ArticleDOI
Prenatal screening for preeclampsia: the roles of placental growth factor and pregnancy–associated plasma protein A in the first trimester and placental growth factor and soluble fms-like tyrosine kinase 1–placental growth factor ratio in the early second trimester
Tianhua Huang,Shamim Rashid,Megan Priston,E. Rasasakaram,Ellen Mak-Tam,Clare A. Gibbons,Elad Mei-Dan,H M Bedford +7 more
TL;DR: In this paper , a case-control study using frozen residual blood samples from women who had aneuploidy screening and delivered at a tertiary center was used to assess the accuracy of (1) a combination of maternal characteristics, maternal serum pregnancy-associated plasma protein A, and placental growth factor in the screening for preeclampsia in the first trimester; and (2) placenta growth factor or soluble fms-like tyrosine kinase-1-placental growth ratio in the early second trimester.