H
Haijun Yu
Researcher at Chinese Academy of Sciences
Publications - 145
Citations - 11360
Haijun Yu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Metastasis & Immunotherapy. The author has an hindex of 53, co-authored 133 publications receiving 7889 citations. Previous affiliations of Haijun Yu include University of Science and Technology of China & Shenyang Pharmaceutical University.
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Journal ArticleDOI
Recent progress in drug delivery
Chong Li,Jiancheng Wang,Yiguang Wang,Huile Gao,Gang Wei,Yongzhuo Huang,Haijun Yu,Yong Gan,Yongjun Wang,Lin Mei,Huabing Chen,Haiyan Hu,Zhiping Zhang,Yiguang Jin +13 more
TL;DR: This review provides a concise overview of current progress in this research area through its focus on the delivery strategies, construction techniques and specific examples.
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Liposomes Coated with Isolated Macrophage Membrane Can Target Lung Metastasis of Breast Cancer
TL;DR: The wrapping of a drug-carrying liposome with an isolated macrophage membrane to improve delivery to metastatic sites and the results provide a biomimetic strategy via the biological properties of macrophages to enhance the medical performance of a nanoparticle in vivo for treating cancer metastasis.
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Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors.
Huiping Sun,Huiping Sun,Jinghan Su,Qingshuo Meng,Qi Yin,Lingli Chen,Wangwen Gu,Pengcheng Zhang,Zhiwen Zhang,Haijun Yu,Siling Wang,Yaping Li +11 more
TL;DR: A unique biomimetic drug-delivery system composed of 4T1-breast-cancer-cell membranes and paclitaxel-loaded polymeric nanoparticles (PPNs) (cell-membrane-coated PPNs) demonstrates superior interactions to its source tumor cells and elongated blood circulation, and displays highly cell-specific targeting of the homotypic primary tumor and metastases.
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Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy
Dangge Wang,Tingting Wang,Jianping Liu,Haijun Yu,Shi Jiao,Bing Feng,Fangyuan Zhou,Yuanlei Fu,Qi Yin,Pengcheng Zhang,Zhiwen Zhang,Zhaocai Zhou,Yaping Li +12 more
TL;DR: It is demonstrated that PDT-mediated cancer immunotherapy can be augmented by PD-L1 knockdown (KD) in tumor cells, and results suggest that acid-activatable micelleplexes utilizing PDT-induced cancer Immunotherapy are more effective when combined with siRNA-mediated PD- L1 blockade.
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Smart pH-sensitive and temporal-controlled polymeric micelles for effective combination therapy of doxorubicin and disulfiram.
TL;DR: The smart co-delivery system was very effective in enhancing the cytotoxicity by increasing the intracellular accumulation of DOX and promoting the apoptotic response, and showed the most effective inhibitory effect on the growth of drug-resistant breast cancer xenografts as compared to other combinations of both drugs.