H
Hajime Ohigashi
Researcher at Fukui Prefectural University
Publications - 72
Citations - 1915
Hajime Ohigashi is an academic researcher from Fukui Prefectural University. The author has contributed to research in topics: Protein kinase C & Isozyme. The author has an hindex of 23, co-authored 72 publications receiving 1764 citations. Previous affiliations of Hajime Ohigashi include Kyoto Prefectural University of Medicine & Kyoto University.
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Ursolic acid : An anti-and pro-inflammatory triterpenoid
TL;DR: Ursolic acid (UA), a natural pentacyclic triterpenoid carboxylic acid, is the major component of some traditional medicine herbs and is well known to possess a wide range of biological functions that are able to counteract endogenous and exogenous biological stimuli.
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Bitter steroid glucosides, vernoniosides A1, A2, and A3, and related B1 from a possible medicinal plant, Vernonia amygdalina, used by wild chimpanzees.
Mitsuo Jisaka,Hajime Ohigashi,Teruyoshi Takagaki,Hitosi Nozaki,Toshiji Tada,Mitsuru Hirota,Ryozo Irie,Michael A. Huffman,Toshisada Nishida,Mikio Kaji,Koichi Koshimizu +10 more
TL;DR: In this article, from Vernonia amygdalina, a possible medicinal plant used by wild chimpanzees, three bitter steroid glucosides, vernoniosides A1, A2, and A3, and a nonbitter glucoside B1, were isolated.
Journal ArticleDOI
Bitter Steroid Glucosides, Vernoniosides A1, A2, and A3, and Related B1 from a Possible Medicinal Plant, Vernonia amygdalina, Used by Wild Chimpanzees.
Mitsuo Jisaka,Hajime Ohigashi,Teruyoshi Takagaki,Hitosi Nozaki,Toshiji Tada,Mitsuru Hirota,Ryozo Irie,Michael A. Huffman,Toshisada Nishida,Mikio Kaji,Koichi Koshimizu +10 more
TL;DR: In this paper, from Vernonia amygdalina, a possible medicinal plant used by wild chimpanzees, three bitter steroid glucosides, vernoniosides A1, A2, and A3, and a nonbitter glucoside B1, were isolated.
Journal ArticleDOI
Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice
TL;DR: In this paper, the authors determined serum levels of adipocytokines in mice with azoxymethane (AOM)- and dextran sulfate sodium (DSS)-induced colon carcinogenesis.
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Synthesis and Phorbol Ester Binding of the Cysteine-rich Domains of Diacylglycerol Kinase (DGK) Isozymes DGKγ AND DGKβ ARE NEW TARGETS OF TUMOR-PROMOTING PHORBOL ESTERS
Mayumi Shindo,Kazuhiro Irie,Akiko Masuda,Hajime Ohigashi,Yasuhito Shirai,Kei Miyasaka,Naoaki Saito +6 more
TL;DR: Results indicate that 12-O-tetradecanoylphorbol 13-acetate binds to C1A of DGKγ to cause its translocation and is associated with the irreversible translocation of whole rat-DGKγ and its C1B deletion mutant from the cytoplasm to the plasma membrane of CHO-K1 cells.