H
Hande Gurer
Researcher at Missouri University of Science and Technology
Publications - 9
Citations - 1292
Hande Gurer is an academic researcher from Missouri University of Science and Technology. The author has contributed to research in topics: Malondialdehyde & Oxidative stress. The author has an hindex of 9, co-authored 9 publications receiving 1237 citations. Previous affiliations of Hande Gurer include University of Missouri & Hacettepe University.
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Journal ArticleDOI
Can Antioxidants Be Beneficial in the Treatment of Lead Poisoning
Hande Gurer,Nuran Ercal +1 more
TL;DR: Data suggest that antioxidants may play an important role in abating some hazards of lead, and that restoration of a cell's antioxidant capacity appears to provide a partial remedy.
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Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats
TL;DR: In vivo evidence is provided supporting the hypothesis that lead induces oxidative stress in RBCs, which is reversible by treatment with a thiol antioxidant (NAC), as well as a chelating agent (succimer).
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Antioxidant effect of taurine against lead-induced oxidative stress.
TL;DR: Taurine seems to be capable of fortifying cells against lead-induced oxidative attack without decreasing lead levels, and administration of taurine, accompanied by a chelating agent, might increase its effectiveness in the treatment of lead poisoning.
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Antioxidant role of α-lipoic acid in lead toxicity
TL;DR: Investigation of the efficacy of lipoic acid in rebalancing the increased prooxidant/antioxidant ratio in lead-exposed Chinese hamster ovary cells and Fischer 344 rats found it to be a good candidate for therapeutic intervention of lead poisoning, in combination with a chelator, rather than as a sole agent.
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Pro-oxidant effects of δ-aminolevulinic acid (δ -ALA) on Chinese hamster ovary (CHO) cells
TL;DR: The hypothesis that δ-ALA accumulation in Chinese hamster ovary (CHO) cells contributes to the cumulative oxidative challenge of lead poisoning as indicated by the oxidative stress parameters glutathione (GSH), glutathion disulfide (GSSG), malondialdehyde equivalents (MDA), and catalase (CAT) is tested.