Journal ArticleDOI
Can Antioxidants Be Beneficial in the Treatment of Lead Poisoning
Hande Gurer,Nuran Ercal +1 more
TLDR
Data suggest that antioxidants may play an important role in abating some hazards of lead, and that restoration of a cell's antioxidant capacity appears to provide a partial remedy.About:
This article is published in Free Radical Biology and Medicine.The article was published on 2000-11-15. It has received 524 citations till now. The article focuses on the topics: Oxidative stress & Lead poisoning.read more
Citations
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Journal ArticleDOI
Advances in metal-induced oxidative stress and human disease
Klaudia Jomová,Marian Valko +1 more
TL;DR: An overview of redox and non-redox metal-induced formation of free radicals and the role of oxidative stress in toxic action of metals is provided.
Journal Article
Heavy metal induced oxidative stress & its possible reversal by chelation therapy.
TL;DR: A comprehensive account of recent developments in the research on heavy metal poisoning particularly the role of oxidative stress/free radicals in the toxic manifestation is attempted, an update about the recent strategies for the treatment with chelating agents and a possible beneficial role of antioxidants supplementation to achieve the optimum effects are attempted.
Journal ArticleDOI
Prevalence of exposure of heavy metals and their impact on health consequences
TL;DR: The global contamination of drinking water with heavy metals is discussed to assess the health hazards associated with consumption of heavy metal‐contaminated water and a relationship between exposure limits and ultimate responses produced has been reviewed.
Journal ArticleDOI
Arsenic-induced oxidative stress and its reversibility
TL;DR: This review summarizes the literature describing the molecular mechanisms of arsenic-induced oxidative stress, its relevant biomarkers, and its relation to various diseases, including preventive and therapeutic strategies and updates the reader on recent advances in chelation therapy and newer therapeutic strategies suggested to treat arsenic- induced oxidative damage.
Book ChapterDOI
Lead Uptake, Toxicity, and Detoxification in Plants
TL;DR: The purpose of this review is to describe how plants take lead up and to link such uptake to the ecotoxicity of lead in plants, and to address the mechanisms by which plants or plant systems detoxify lead.
References
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Book
Free radicals in biology and medicine
TL;DR: 1. Oxygen is a toxic gas - an introduction to oxygen toxicity and reactive species, and the chemistry of free radicals and related 'reactive species'
Journal ArticleDOI
Goodman and Gilman's the Pharmacological Basis of Therapeutics
William H. Stigelman,Pharm D. +1 more
Journal ArticleDOI
alpha-Lipoic acid as a biological antioxidant.
TL;DR: The properties of lipoate are reviewed in terms of reactions with reactive oxygen species; interactions with other antioxidants; beneficial effects in oxidative stress models or clinical conditions.
Journal ArticleDOI
The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid.
TL;DR: N-acetylcysteine is a powerful scavenger of hypochlorous acid (H--OCl); low concentrations are able to protect alpha 1-antiproteinase against inactivation by HOCl.