H
Hanna Laine
Researcher at University of Turku
Publications - 52
Citations - 2865
Hanna Laine is an academic researcher from University of Turku. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 28, co-authored 52 publications receiving 2687 citations. Previous affiliations of Hanna Laine include Turku University Hospital & National Institutes of Health.
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Journal ArticleDOI
A Nationwide Survey of Mortality in Acromegaly
Ritva Kauppinen-Mäkelin,Timo Sane,Antti Reunanen,Matti Välimäki,Leo Niskanen,Helene Markkanen,Eliisa Löyttyniemi,Tapani Ebeling,Pia Jaatinen,Hanna Laine,Pirjo Nuutila,Pasi I. Salmela,Jorma Salmi,Ulf-Håkan Stenman,Jorma Viikari,Erkki Voutilainen +15 more
TL;DR: The posttreatment basal GH concentration less than 2.5 microg/liter in acromegalic patients is associated with a normal lifespan, and excess mortality is confined to poorly controlled patients and possibly those who have received conventional radiotherapy.
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Coronary Flow Reserve Is Reduced in Young Men With IDDM
Olli-Pekka Pitkänen,Pirjo Nuutila,Olli T. Raitakari,Tapani Rönnemaa,Pertti J Koskinen,Hidehiro Iida,Terho Lehtimäki,Hanna Laine,Teemu Takala,Jorma Viikari,Juhani Knuuti +10 more
TL;DR: Coronary flow reserve is impaired in young adult males with IDDM and no or minimal microvascular complications and without any evidence of coronary heart disease, which implies early impairment of coronary vascular reactivity in IDDM patients, which may represent an early precursor of future coronary heart diseases or contribute to the pathogenesis of diabetic cardiomyopathy.
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Gender and Insulin Sensitivity in the Heart and in Skeletal Muscles: Studies Using Positron Emission Tomography
Pirjo Nuutila,M J Knuuti,Maija Mäki,Hanna Laine,Ulla Ruotsalainen,Mika Teräs,Merja Haaparanta,Olof Solin,Hannele Yki-Järvinen +8 more
TL;DR: Women are more sensitive to insulin than equally fit men because of enhanced muscle but not heart insulin sensitivity, and gender and VO2max together explained 68% of the variation in femoral muscle glucose uptake.
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Early impairment of coronary flow reserve in young men with borderline hypertension
Hanna Laine,Olli T. Raitakari,Harri Niinikoski,Olli Pitkänen,Hidehiro Iida,Jorma Viikari,Pirjo Nuutila,Juhani Knuuti +7 more
TL;DR: These results demonstrate reduced coronary reactivity present in young asymptomatic men with borderline hypertension and no signs of hypertension-induced angina or left ventricular hypertrophy.
Journal ArticleDOI
Coronary flow reserve: measurement with transthoracic Doppler echocardiography is reproducible and comparable with positron emission tomography
Markku Saraste,Juha Koskenvuo,Juhani Knuuti,Jyri O Toikka,Hanna Laine,Pekka Niemi,Hajime Sakuma,Jaakko Hartiala +7 more
TL;DR: In this article, the authors used transthoracic Doppler echocardiography (TTE) and positron emission tomography (PET) to measure coronary flow reserve.