Hanne Kolsrud Hustoft

TL;DR: The failure in the search for biomarkers as indicators of disease, the difficulties of protein arrays, the uncertainty of quantification in “shotgun proteomics”, database shortcomings, and finally the huge disappointment in the area of drug discovery are addressed.

TL;DR: Recommendations regarding optimizing and evaluating the tryptic digestion for both targeted and comprehensive proteomics are given, and a digestion method suitable as the first method for newcomers in Comprehensive proteomics is suggested.

TL;DR: Initial results point to automated solutions for fast and very sensitive MS based proteomics, especially for samples of limited size, as well as on-line digestion/separation systems.

TL;DR: A taxonomical study of 90 isolates of lactobacilli isolated from soft and hard carious dentine of 70 deciduous molars and shotgun mass mapping has unique potential for the analysis of Lactobacillus strains on subspecies level.

TL;DR: Proteome analysis following STLC treatment revealed 33 differentially regulated proteins of various cellular processes, 31 of which can be linked to apoptotic cell death, Interestingly, four identified proteins, chromobox protein homolog, RNA‐binding Src associated in mitosis 68 kDa protein, stathmin, and translationally controlled tumor protein can belinked to mitotic and apoptotic processes.