Steven Ray Wilson

TL;DR: A novel small molecule inhibitor of the β-catenin signaling pathway, JW55, that functions via inhibition of the PARP domain of tankyrase 1 and tankyrases 2 (TNKS1/2), regulators of theβ-catanin destruction complex is identified.

TL;DR: 2 new small molecules are identified that specifically inhibit canonical Wnt pathway at the level of the destruction complex in human colorectal cancer cells and inhibited the growth of tumor cells in both a mouse xenograft model of CRC and in Apc(Min) mice.

TL;DR: The Fenton and the sono-Fenton decomposition of BPA showed that ultrasound irradiation of wastewater improved the wet oxidation process of 25 mg l(-1) BPA solutions.

TL;DR: Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior and its capacity to shift chemical forms and bind to other molecules make this molecule difficult to work with and to measure.

TL;DR: On-line solid phase extraction (SPE)-liquid chromatography (LC) allows for automated, sensitive, precise and selective bioanalysis, and certain columns, configurations and hardware can improve robustness.