S
Stefan Krauss
Researcher at University of Oslo
Publications - 137
Citations - 15339
Stefan Krauss is an academic researcher from University of Oslo. The author has contributed to research in topics: Wnt signaling pathway & LRP6. The author has an hindex of 54, co-authored 136 publications receiving 14415 citations. Previous affiliations of Stefan Krauss include Lund University & University of Cambridge.
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Journal ArticleDOI
A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos
TL;DR: The existence of an hh-related gene family in the zebrafish, Brachydanio rerio, that is expressed in the notochord, floor plate, and posterior fin mesoderm, tissues associated with polarizing activities in various vertebrate embryos is described.
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Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice
James Palacino,Dijana Sagi,Matthew S. Goldberg,Stefan Krauss,Claudia Motz,Maik A. Wacker,Joachim Klose,Jie Shen +7 more
TL;DR: Analysis of proteomic, genetic, and physiological analyses reveal an essential role for parkin in the regulation of mitochondrial function and provide the first direct evidence of mitochondrial dysfunction and oxidative damage in the absence of nigral degeneration in a genetic mouse model of Parkinson's disease.
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Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes
Chen-Yu Zhang,Gyorgy Baffy,Gyorgy Baffy,Pascale Perret,Stefan Krauss,Odile D. Peroni,Danica Grujic,Thilo Hagen,Antonio Vidal-Puig,Olivier Boss,Young-Bum Kim,Xin Xiao Zheng,Michael B. Wheeler,Gerald I. Shulman,Catherine B. Chan,Bradford B. Lowell +15 more
TL;DR: Results establish UCP2 as a key component of β cell glucose sensing, and as a critical link between obesity, β cell dysfunction, and type 2 diabetes.
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Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1
Pere Puigserver,James Rhee,Jiandie D. Lin,Zhidan Wu,J. Cliff Yoon,Chen-Yu Zhang,Stefan Krauss,Vamsi K. Mootha,Bradford B. Lowell,Bruce M. Spiegelman +9 more
TL;DR: It is shown here that many cytokines activate the transcriptional PPAR gamma coactivator-1 (PGC-1) through phosphorylation by p38 kinase, resulting in stabilization and activation of PGC-1 protein.
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Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse
Mehul T. Dattani,Juan Pedro Martinez-Barbera,Paul Q. Thomas,Joshua M. Brickman,Raj Gupta,Inga-Lill Mårtensson,Håkan Toresson,Margaret Fox,Jerry Wales,Peter C. Hindmarsh,Stefan Krauss,Rosa S. P. Beddington,Iain C. A. F. Robinson +12 more
TL;DR: An important role for Hesx1/HESX1 in forebrain, midline and pituitary development in mouse and human is suggested.