H
Hanne Kolsrud Hustoft
Researcher at University of Oslo
Publications - 9
Citations - 360
Hanne Kolsrud Hustoft is an academic researcher from University of Oslo. The author has contributed to research in topics: Protein digestion & Proteomics. The author has an hindex of 9, co-authored 9 publications receiving 342 citations. Previous affiliations of Hanne Kolsrud Hustoft include Norwegian University of Life Sciences.
Papers
More filters
Book ChapterDOI
A Critical Review of Trypsin Digestion for LC-MS Based Proteomics
Hanne Kolsrud Hustoft,Helle Malerod,Steven Ray Wilson,Léon Reubsaet,Elsa Lundanes,Tyge Greibrokk +5 more
TL;DR: The failure in the search for biomarkers as indicators of disease, the difficulties of protein arrays, the uncertainty of quantification in “shotgun proteomics”, database shortcomings, and finally the huge disappointment in the area of drug discovery are addressed.
Journal ArticleDOI
Critical assessment of accelerating trypsination methods.
TL;DR: Recommendations regarding optimizing and evaluating the tryptic digestion for both targeted and comprehensive proteomics are given, and a digestion method suitable as the first method for newcomers in Comprehensive proteomics is suggested.
Journal ArticleDOI
Open Tubular Lab-On-Column/Mass Spectrometry for Targeted Proteomics of Nanogram Sample Amounts
Hanne Kolsrud Hustoft,Tore Vehus,Ole Kristian Brandtzaeg,Stefan Krauss,Tyge Greibrokk,Steven Ray Wilson,Elsa Lundanes +6 more
TL;DR: Initial results point to automated solutions for fast and very sensitive MS based proteomics, especially for samples of limited size, as well as on-line digestion/separation systems.
Journal ArticleDOI
Shotgun mass mapping of Lactobacillus species and subspecies from caries related isolates by MALDI-MS.
TL;DR: A taxonomical study of 90 isolates of lactobacilli isolated from soft and hard carious dentine of 70 deciduous molars and shotgun mass mapping has unique potential for the analysis of Lactobacillus strains on subspecies level.
Journal ArticleDOI
Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5
Frank Kozielski,Dimitrios A. Skoufias,Rose-Laure Indorato,Yasmina Saoudi,Peter R. Jungblut,Hanne Kolsrud Hustoft,Margarita Strozynski,Bernd Thiede +7 more
TL;DR: Proteome analysis following STLC treatment revealed 33 differentially regulated proteins of various cellular processes, 31 of which can be linked to apoptotic cell death, Interestingly, four identified proteins, chromobox protein homolog, RNA‐binding Src associated in mitosis 68 kDa protein, stathmin, and translationally controlled tumor protein can belinked to mitotic and apoptotic processes.