H
Hans G. Beger
Researcher at University of Ulm
Publications - 359
Citations - 26586
Hans G. Beger is an academic researcher from University of Ulm. The author has contributed to research in topics: Pancreatitis & Pancreatic disease. The author has an hindex of 85, co-authored 359 publications receiving 25553 citations. Previous affiliations of Hans G. Beger include University of Turku & Otto-von-Guericke University Magdeburg.
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Journal ArticleDOI
A Randomized Trial of Chemoradiotherapy and Chemotherapy after Resection of Pancreatic Cancer
John P. Neoptolemos,Deborah D. Stocken,Helmut Friess,Claudio Bassi,Janet A. Dunn,Helen Hickey,Hans G. Beger,Laureano Fernández-Cruz,Christos Dervenis,François Lacaine,Massimo Falconi,Paolo Pederzoli,Akos F. Pap,David Spooner,David J. Kerr,Markus W. Büchler +15 more
TL;DR: Adjuvant chemotherapy has a significant survival benefit in patients with resected pancreatic cancer, whereas adjuvant chemoradiotherapy has a deleterious effect on survival.
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Identification, Culture, and Characterization of Pancreatic Stellate Cells in Rats and Humans
Max G. Bachem,Erik Schneider,Hans Groß,Hans Weidenbach,Roland M. Schmid,Andre Menke,Marco Siech,Hans G. Beger,Adolf Grünert,Guido Adler +9 more
TL;DR: The identification of retinoid-containing pancreatic stellate cells (PSCs) in rat and human pancreas are described, and morphological and biochemical similarities to hepatic stellates cells are shown, suggesting that PSCs participate in the development of Pancreas fibrosis.
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Bacterial contamination of pancreatic necrosis. A prospective clinical study.
TL;DR: It is demonstrated that bacterial contamination of pancreatic necrosis occurs early and frequently, causing a significant increase in morbidity and mortality, particularly when it develops in the initial stages of the attack.
Journal ArticleDOI
Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
Max G. Bachem,Marion Schünemann,Marco Ramadani,Marco Siech,Hans G. Beger,Andreas Buck,Shaoxia Zhou,Alexandra Schmid-Kotsas,Guido Adler +8 more
TL;DR: Pancreatic stellate cells strongly support tumor growth in the nude mouse model and the increased deposition of connective tissue in pancreatic carcinoma is the result of a paracrine stimulation of pancreatic stllate cells by carcinoma cells.
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Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial.
John P. Neoptolemos,Deborah D. Stocken,Janet A. Dunn,J. Almond,Hans G. Beger,Paolo Pederzoli,Claudio Bassi,Christos Dervenis,Laureano Fernández-Cruz,François Lacaine,John A. C. Buckels,M. Deakin,Fawzi Adab,Robert Sutton,Clem W. Imrie,Ingemar Ihse,Tibor Tihanyi,Attila Oláh,Sergio Pedrazzoli,David Spooner,David J. Kerr,Helmut Friess,Markus W. Büchler +22 more
TL;DR: Resection margin-positive pancreatic tumors represent a biologically more aggressive cancer; these patients benefit from resection and adjuvant chemotherapy but not chemoradiation; the magnitude of benefit for chemotherapy treatment is reduced for patients with R1 margins versus those with R0 margins.