H
Helen Hickey
Researcher at University of Liverpool
Publications - 51
Citations - 4369
Helen Hickey is an academic researcher from University of Liverpool. The author has contributed to research in topics: Clinical trial & Randomized controlled trial. The author has an hindex of 19, co-authored 51 publications receiving 3704 citations. Previous affiliations of Helen Hickey include National Health Service.
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Journal ArticleDOI
A Randomized Trial of Chemoradiotherapy and Chemotherapy after Resection of Pancreatic Cancer
John P. Neoptolemos,Deborah D. Stocken,Helmut Friess,Claudio Bassi,Janet A. Dunn,Helen Hickey,Hans G. Beger,Laureano Fernández-Cruz,Christos Dervenis,François Lacaine,Massimo Falconi,Paolo Pederzoli,Akos F. Pap,David Spooner,David J. Kerr,Markus W. Büchler +15 more
TL;DR: Adjuvant chemotherapy has a significant survival benefit in patients with resected pancreatic cancer, whereas adjuvant chemoradiotherapy has a deleterious effect on survival.
Journal ArticleDOI
Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis
Athimalaipet V Ramanan,Andrew D. Dick,Ashley P Jones,Andrew McKay,Paula R Williamson,Sandrine Compeyrot-Lacassagne,Ben Hardwick,Helen Hickey,Dyfrig A. Hughes,Patricia Woo,Diana Benton,Clive Edelsten,Michael W. Beresford +12 more
TL;DR: Adalimumab therapy controlled inflammation and was associated with a lower rate of treatment failure than placebo among children and adolescents with active JIA‐associated uveitis who were taking a stable dose of methotrexate.
Journal ArticleDOI
The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial
Michael D. Jenkinson,Michael D. Jenkinson,Mohsen Javadpour,Brian Haylock,Bridget Young,Helen Gillard,Jacqui Vinten,Jacqui Vinten,Helen Bulbeck,Kumar Das,Michael A. Farrell,Seamus Looby,Helen Hickey,Mattheus Preusser,Conor Mallucci,Conor Mallucci,Dyfrig A. Hughes,Carrol Gamble,Damien C. Weber +18 more
TL;DR: ROAM/EORTC-1308 is the first multi-centre randomised controlled trial designed to determine whether early adjuvant radiotherapy reduces the risk of tumour recurrence following complete surgical resection of atypical meningioma.
Journal ArticleDOI
Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial
Mark D Lyttle,Mark D Lyttle,Naomi Rainford,Carrol Gamble,Shrouk Messahel,Amy Humphreys,Helen Hickey,Kerry Woolfall,Louise Roper,Joanne Noblet,Elizabeth Lee,Sarah Potter,Paul Tate,Anand Iyer,Vicki Evans,Richard Appleton,Matthew. Pereira,Susie. Hardwick,Rachel. Greenwood-Bibby,Mark. Buchanan,Lucy. Lewis,Sharon. Hughes,Stuart Hartshorn,Louise. Rogers,Juliet. Hopkins,Daphin. Fernandez,Holly R. Lavigne-Smith,Phoebe. Moulsdale,Alice C. Smith,Tracey. Bingham,James Ross,Natasha. Ramsey,Jo. Hacking,Niall. Mullen,Paul P. Corrigan,Sarah. Prudhoe,Hani. Faza,Gisela. Robinson,Rachel C. Sunley,Coral J. Smith,Vanessa. Unsworth,John. Criddle,Martin Laque,Alyce B. Sheedy,Mark S. Anderson,Kathryn. Bell,Kirsty. Devine,Alex Scott,Ramesh Kumar,Sonia. Armstrong,Emer. Sutherland,Fleur. Cantle,Sinead. Helyer,Paul. Riozzi,Hannah. Cotton,Alice J. Downes,Helen. Mollard,Damian Roland,Felix. Hay,Christopher. Gough,Sonya. Finucane,Catherine Bevan,Rebecca. Ramsay,Emily. Walton,Julie Ann Maney,Elizabeth. Dalzell,Muriel. Millar,Rachel J. Howells,Andy. Appelboam,Daisy. Mackle,Jennie. Small,Ashleigh. Neil,Vince. Choudhery,Stewart. MacLeod,Jen. Browning,Thomas. O'Neill,Julia Grahamslaw,Ami. Parikh,Imogen Skene,Rhys. Thomas,Katherine. Potier de la Morandiere,Jill L. Wilson,Donna. Danziger,Derek. Burke,Shammi. Ramlakhan,Jayne. Evans,Julie. Morcombe,Stuart. Gormley,Jason M. Barling,Katrina Cathie,Jane. Bayreuther,Ruth. Ensom,Yasser. Iqbal,Sarah. Rounding,Joanne. Mulligan,Claire. Bell,Shona. McLellan,Shona. Leighton,Tina. Sajjanhar,Maggie. Nyirenda,Laura. Crome,Neil. Williamson,Anastasia. Alcock,Sara. Edwards,Jeffrey A. Morgan,Colin V. E. Powell,Chaniyil A. Ramesh,Solomon. Kamal-Uddin,Mike. Linney,Katia. Vamvakiti,Sharon. Floyd,Gill. Hobden +111 more
TL;DR: The results suggest levetiracetam could be an appropriate alternative to phenytoin as the first-choice, second-line anticonvulsant in the treatment of paediatric convulsive status epilepticus.
Journal ArticleDOI
A patient and public involvement (PPI) toolkit for meaningful and flexible involvement in clinical trials – a work in progress
Heather Bagley,Hannah Short,Nicola Harman,Helen Hickey,Carrol Gamble,Kerry Woolfall,Bridget Young,Paula R Williamson +7 more
TL;DR: A developing toolkit to support clinical trials teams to undertake effective and meaningful PPI is described, which provides a developing ‘off the shelf’ resource to support trial teams with limited resources in undertaking PPI.