H
Hans van Eenennaam
Researcher at Radboud University Nijmegen
Publications - 6
Citations - 669
Hans van Eenennaam is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: RNase MRP & Ribonucleoprotein. The author has an hindex of 6, co-authored 6 publications receiving 622 citations.
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Journal ArticleDOI
Mutations in the RNA Component of RNase MRP Cause a Pleiotropic Human Disease, Cartilage-Hair Hypoplasia
Maaret Ridanpää,Hans van Eenennaam,Katarina Pelin,Robert B. Chadwick,Cheryl K. Johnson,Bo Yuan,Walther J. vanVenrooij,Ger J. M. Pruijn,Riika Salmela,Susanna Rockas,Outi Mäkitie,Ilkka Kaitila,Albert de la Chapelle +12 more
TL;DR: It is concluded that mutations in RMRP cause CHH by disrupting a function of RNase MRP RNA that affects multiple organ systems.
Journal ArticleDOI
Identity of the RNase MRP- And RNase P-associated Th/To Autoantigen
Hans van Eenennaam,Judith Vogelzangs,Dorien Lugtenberg,Frank H J van den Hoogen,Walther J. van Venrooij,Ger J. M. Pruijn +5 more
TL;DR: It is demonstrated that almost all tested anti-Th/To+ patient sera contained autoantibodies to Rpp25 and hPop1, indicating that these proteins harbor the most frequently targeted Th/To determinants.
Journal ArticleDOI
hPop5, a protein subunit of the human RNase MRP and RNase P endoribonucleases.
Hans van Eenennaam,Dorien Lugtenberg,Judith Vogelzangs,Walther J. van Venrooij,Ger J. M. Pruijn +4 more
TL;DR: Using affinity-purified anti-hPop5 antibodies, it is demonstrated that the endogenous hPop5 protein is localized in the nucleus and accumulates in the nucleolus, which is consistent with its association with RNase MRP and RNase P.
Journal ArticleDOI
Basic helix–loop–helix transcription factor Tcfl5 interacts with the Calmegin gene promoter in mouse spermatogenesis
Michel Siep,Esther Sleddens-Linkels,Sabine Mulders,Hans van Eenennaam,Evelyne Wassenaar,Wiggert A. van Cappellen,Jos W. Hoogerbrugge,J. Anton Grootegoed,Willy M. Baarends +8 more
TL;DR: To identify testis-specific transcription factors that control expression of the Clgn gene in spermatogenesis, a yeast one-hybrid screening resulted in the identification of mouse Tcfl5 as a candidate Clgn promoter-binding protein.
Journal ArticleDOI
hPop4: a new protein subunit of the human RNase MRP and RNase P ribonucleoprotein complexes.
TL;DR: Data show that a protein that represents the human counterpart of the yeast Pop4p protein is identified, and it is shown that anti-hPop4 immunoprecipitates possess RNase P enzymatic activity.