Willy M. Baarends

TL;DR: The results indicate that FSH and estrogens may play a role in the down-regulation of AMH and AMHRII mRNA expression in vivo when small antral follicles differentiate into large antRAL follicles.

TL;DR: It is proposed that SYCP1 has a coordinating role, and ensures formation of crossovers in meiotic chromosome behavior and recombination, and Unexpectedly, Sycp1(-/-) spermatocytes did not form XY bodies.

TL;DR: This review highlights the current knowledge on post-meiotic chromatin reorganization and reveals for the first time intriguing parallels in this process in Drosophila and mammals and illustrates the possible mechanisms that lead from a histone-based chromatin to a mainly protamine-based structure during spermatid differentiation.

TL;DR: The phenotype of the first animal mutant in the ubiquitin pathway is reported: inactivation of the hHR6B-homologous gene in mice causes male infertility, and this findings provide a parallel between yeast sporulation and mammalian spermatogenesis and strongly implicate h HR6-dependent ubiquitination in chromatin remodeling.

TL;DR: Results show that, as in S. cerevisiae, MmRAD52 is involved in recombination, although the repair of DNA damage is not affected upon inactivation, indicating that Mm RAD52 may be involved in certain types of DSB repair processes and not in others.