H
Hao Chen
Researcher at Inner Mongolia University for Nationalities
Publications - 9
Citations - 70
Hao Chen is an academic researcher from Inner Mongolia University for Nationalities. The author has contributed to research in topics: Zebrafish & Medicine. The author has an hindex of 3, co-authored 6 publications receiving 14 citations.
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Journal ArticleDOI
Long-term oxytetracycline exposure potentially alters brain thyroid hormone and serotonin homeostasis in zebrafish.
Jiawei Li,Ting Dong,Tharushi Prabha Keerthisinghe,Hao Chen,Ming Li,Chu Wenqing,Jingfeng Yang,Zongfu Hu,Shane A. Snyder,Wu Dong,Mingliang Fang +10 more
TL;DR: It is suggested that long-term OTC exposure not only alters gut microbiome but also changes thyroid hormone and serotonin homeostasis in the brain via "chemical-gut-brain" axis.
Journal ArticleDOI
Aconitine disrupts serotonin neurotransmission via 5-hydroxytryptamine receptor in zebrafish embryo
Hao Chen,Feng Wang,Xuan Ni,Yi Rigui,Yuxia Bai,Liang Xu,Jingfeng Yang,Xuefu Zhang,Jiang Deng,Jiawei Li,Xiaoyu Yin,Wuliji Ao,Kevin W.H. Kwok,Wu Dong +13 more
TL;DR: Investigation of neurotoxicity of aconitine to zebrafish embryos in early development in relation to serotonin regulation suggests that neurotoxicity caused by ac onitine is mediated through the 5‐HT receptor.
Journal ArticleDOI
Chiral toxicity of muscone to embryonic zebrafish heart.
Ming Li,Liang Yao,Hao Chen,Xuan Ni,Yao Xu,Wengjing Dong,Mingliang Fang,Da Chen,Aowuliji,Liang Xu,Baoquan Zhao,Jiang Deng,Kevin Wh. Kwok,Jingfeng Yang,Wu Dong +14 more
TL;DR: Zebrafish as an animal model showed that both compounds were acutely toxic to zebrafish embryos causing mortality, decreased hatching rate, pericardial edema, and decreased heart beat rate.
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Effects of ferulic acid on muscle development and intestinal microbiota of zebrafish
Xiaoyu Yin,Wuyun Liu,Hao Chen,Chelimuge Qi,Hongsong Chen,Huaxin Niu,Jingfeng Yang,Kevin W.H. Kwok,Wu Dong +8 more
TL;DR: Zhang et al. as discussed by the authors evaluated both safety and mechanism of efficacy in zebrafish model and concluded that FA can be a safe growth promotor in fish particularly in skeletal muscles.
Journal ArticleDOI
Effect of dark environment on intestinal flora and expression of genes related to liver metabolism in zebrafish (Danio rerio).
TL;DR: In this article, the effects of dark environment on intestinal flora and expression of genes related to liver metabolism in zebrafish were explored using sequencing analysis of intestinal bacteria and liver gene expression.