Hao Lu

TL;DR: The results strongly implied the physiological importance of CD39 expression and suggested that manipulation ofCD39hi Tregs might represent a novel strategy for the treatment of autoimmune diseases.

TL;DR: Myeloid Notch1 deficiency activates the ras homolog gene family member A/ROCK pathway and exacerbates hepatocellular injury by inhibiting transcriptional repressor Hes1 and inducing scaffold protein JSAP1 in IR‐triggered liver inflammation and imply the therapeutic potential for the management of organ IR injury in transplant recipients.

TL;DR: In aggregate, these studies provide a new approach that uses miR-142-3p knockdown to increase tTreg cell efficacy by increasing ATG16L1 mRNA and protein and the autophagy process.

TL;DR: It is indicated that CTLA-4 +49 G/A (rs231775) is associated with the susceptibility of autoimmune disease, and might be utilized as a diagnostic biomarker in both Asian and Caucasian populations.

TL;DR: It was proved that HULC regulates the function of Tregs through down-regulated the level of p18 directly directly in HBV-related liver cirrhosis.