Harlan M. Krumholz

TL;DR: The authors identified seven preferred attributes of statistical models used for publicly reported outcomes, including clear and explicit definition of an appropriate patient sample, clinical coherence of model variables, sufficiently high-quality and timely data, designation of appropriate reference time before which covariates are derived and after which outcomes are measured, use of appropriate outcome and a standardized period of outcome assessment, application of an analytical approach that takes into account the multilevel organization of data, and disclosure of the methods used to compare outcomes.

TL;DR: In this paper, an appropriateness review was conducted for radionuclide cardiovascular imaging (RNI), specifically gated single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI).

TL;DR: Although there was a significant negative linear relationship between RSMRs and RSRRs for heart failure, the shared variance between them was only 2.9% and the results were similar for subgroups defined by hospital characteristics.

TL;DR: The quality of clinical trial evidence used by the FDA as the basis for recent approvals of novel therapeutic agents varied widely across indications, having important implications for patients and physicians as they make decisions about the use of newly approved therapeutic agents.

TL;DR: Omission of key information during sign-out can have important adverse consequences for patients and health care providers.