Harlan M. Krumholz

TL;DR: Concomitant VTE is not only a marker and potential mediator of increased risk of death among older cancer patients, but patients with a VTE have a marked increasedrisk of major hemorrhage.

TL;DR: The first study from China PEACE, the Retrospective Study of Acute Myocardial Infarction (China PEACE-Retrospective AMI Study), is designed to promote improvements in acute myocardial infarction quality of care by generating knowledge about the characteristics, treatments, and outcomes of patients hospitalized with AMI across a representative sample of Chinese hospitals during the past decade.

TL;DR: hospital staff from higher-performing hospitals described broad, multifaceted strategies to support collaboration with EMS in providing acute myocardial infarction care, and the association of these strategies with hospital performance should be tested quantitatively in a larger representative study.

TL;DR: A dose-response relationship between higher doses and lower mortality is observed, and future studies will need to determine whether this association is causal.

TL;DR: Although cardiovascular surrogate outcomes trials frequently show superiority of the tested intervention, they are infrequently followed by a prominent outcomes trial, and may be more appropriate for excluding benefit from the patient perspective than for identifying it.