H
Harshal Hanumant Nandurkar
Researcher at Monash University
Publications - 127
Citations - 3892
Harshal Hanumant Nandurkar is an academic researcher from Monash University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 30, co-authored 112 publications receiving 3393 citations. Previous affiliations of Harshal Hanumant Nandurkar include Cooperative Research Centre & University of Melbourne.
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Journal ArticleDOI
Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation
Lorraine Robb,Ruili Li,Lynne Hartley,Harshal Hanumant Nandurkar,Harshal Hanumant Nandurkar,Frank Koentgen,C G Begley +6 more
TL;DR: It is shown that female mice with a null mutation of the interleukin-11 receptor alpha chain are infertile because of defective decidualization, revealing a previously unrecognized critical role for IL-11 signaling in female reproduction.
Journal ArticleDOI
Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation
Sarah Kamel,L Horton,Loic Ysebaert,Marie Levade,Kate Burbury,Shuh Ying Tan,Merrole F Cole-Sinclair,John V. Reynolds,Robin Filshie,Steven Schischka,Amit Khot,Shahneen Sandhu,Michael J. Keating,Harshal Hanumant Nandurkar,Constantine S. Tam +14 more
TL;DR: In this article, light transmission aggregometry was used to determine the real-life consequences of BTK platelet blockade in 23 patients receiving ibrutinib treatment, with a significant association between the degree of inhibition and the occurrence of clinical bleeding or bruising.
Journal ArticleDOI
Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation
Karen M. Dwyer,Simon C. Robson,Harshal Hanumant Nandurkar,Duncan J. Campbell,Hilton Gock,Lisa Murray-Segal,Nella Fisicaro,Tharun Mysore,Elizabeth Ann Kaczmarek,Peter J. Cowan,Anthony J. F. D'apice +10 more
TL;DR: Thromboregulatory manifestations in hCD39 transgenic mice suggest important therapeutic potential in clinical vascular disease and in the control of serious thrombotic events that compromise the survival of porcine xenografts in primates.
Journal ArticleDOI
The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.
Jennifer M Dyson,Cindy J. O'Malley,Jelena Becanovic,Adam D. Munday,Michael C. Berndt,Imogen Denise Coghill,Harshal Hanumant Nandurkar,Lisa M Ooms,Christina Anne Mitchell +8 more
TL;DR: It is demonstrated that filamin-dependent SHIP-2 localization critically regulates phosphatidylinositol 3 kinase signaling to the actin cytoskeleton.
Journal ArticleDOI
Adult Mice With Targeted Mutation of the Interleukin-11 Receptor (IL11Ra) Display Normal Hematopoiesis
Harshal Hanumant Nandurkar,Lorraine Robb,David M. Tarlinton,Louise Barnett,Frank Köntgen,Colin Glenn Begley +5 more
TL;DR: In this paper, a null mutation of IL11Ra (IL11Ra−/−) by gene targeting was found in mice with a 50% decrease in hematocrit.