H
Hassan Rahimi
Researcher at Sapienza University of Rome
Publications - 37
Citations - 809
Hassan Rahimi is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Immunotherapy & Antigen. The author has an hindex of 16, co-authored 32 publications receiving 692 citations. Previous affiliations of Hassan Rahimi include University of Pisa.
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Journal ArticleDOI
Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation
Chiara Napoletano,Ilaria Grazia Zizzari,Aurelia Rughetti,Hassan Rahimi,Tatsuro Irimura,Henrik Clausen,Hans H. Wandall,Francesca Belleudi,Filippo Bellati,Luca Pierelli,Luigi Frati,Marianna Nuti +11 more
TL;DR: It is demonstrated that the targeting of MGL receptor on human DCs has an adjuvant effect and that this strategy can be used to design novel anticancer vaccines.
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RFA strongly modulates the immune system and anti-tumor immune responses in metastatic liver patients
Chiara Napoletano,Federica Taurino,Mauro Biffoni,Adriano De Majo,Coscarella G,Filippo Bellati,Hassan Rahimi,Simona Pauselli,Ilenia Pellicciotta,Joy Burchell,Lucio Achille Gaspari,Lucia Ercoli,Piero Rossi,Aurelia Rughetti +13 more
TL;DR: Results indicate that RFA application can exert an activating effect on the immune system in metastatic cancer patients, favouring trafficking of lymphocyte subsets and enhancing tumor antigen specific cellular immune responses.
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Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis
Vincenzo Cardinale,Guido Carpino,Raffaele Gentile,Chiara Napoletano,Hassan Rahimi,Antonio Franchitto,Rossella Semeraro,Marianna Nuti,Paolo Onori,Pasquale Berloco,Massimo Rossi,Daniela Bosco,Roberto Brunelli,A. Fraveto,Cristina Napoli,A. Torrice,M. Gatto,Rosanna Venere,Carlo Bastianelli,Camilla Aliberti,Filippo Maria Salvatori,Luciano Bresadola,Mario Bezzi,Adolfo Francesco Attili,Lola M. Reid,Eugenio Gaudio,Domenico Alvaro +26 more
TL;DR: This report represents proof of the concept that the human fetal biliary tree stem cells are a suitable and large source for cell therapy of liver cirrhosis and represents the basis for forthcoming controlled clinical trials.
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Transfected human dendritic cells to induce antitumor immunity.
Aurelia Rughetti,Mauro Biffoni,Michela Sabbatucci,Hassan Rahimi,Ilenia Pellicciotta,Andrea Fattorossi,Luca Pierelli,Giovanni Scambia,Marialuisa Lavitrano,Luigi Frati,Marianna Nuti +10 more
TL;DR: These protocols were applied to modify dendritic cells in order to express an epithelial tumor-associated antigen, MUC1, and such cells were able to induce in vitro a specific immune response in healthy donors.
Journal ArticleDOI
MGL Receptor and Immunity: When the Ligand Can Make the Difference.
Ilaria Grazia Zizzari,Chiara Napoletano,Federico Battisti,Hassan Rahimi,Salvatore Caponnetto,Luca Pierelli,Marianna Nuti,Aurelia Rughetti +7 more
TL;DR: Modifying Tn-density, the length, and steric structure of the TN-antigens can result in generating immunogens that can efficiently bind to MGL, strongly activate DCs, mimic the effects of a danger signal, and achieve an efficient presentation in HLA classes I and II compartments.