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Hasse Karlsson

Researcher at Turku University Hospital

Publications -  355
Citations -  10130

Hasse Karlsson is an academic researcher from Turku University Hospital. The author has contributed to research in topics: Medicine & Anxiety. The author has an hindex of 43, co-authored 301 publications receiving 8062 citations. Previous affiliations of Hasse Karlsson include Stockholm University & Swedish University of Agricultural Sciences.

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The prevalence of what

TL;DR: This issue of the NJP, three articles on the prevalence of psychiatric disorders are published and depression appeared to be on a continuum where ‘‘proxy’’ measures such as impairment and need for treatment were associated with the intensity of depressed mood.
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Fearing the Disease or the Vaccine: The Case of COVID-19

TL;DR: The role of perceived risk of COVID-19 (i.e., perceived likelihood of infection, perceived disease severity, and disease-related worry) and perceived safety of a prospective vaccine against COvid-19 in predicting intentions to accept a CO VID-19 vaccine is investigated.
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Altered O-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation

TL;DR: In the majority of the active UC patients MUC2 mucin has an altered glycan profile as compared to inactive UC and control patients, which was significantly related to both the degree of inflammation in the biopsies and also to some extent the severity of disease course.
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A complex, but uniform O-glycosylation of the human MUC2 mucin from colonic biopsies analyzed by nanoLC/MSn.

TL;DR: The aim was to identify the MUC2 O-glycans of the sigmoid colon and provide a comprehensive catalog of the O- glycan repertoire and relative amounts in normal individuals were relatively constant.
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The ST6GalNAc-I sialyltransferase localizes throughout the golgi and is responsible for the synthesis of the tumor- associated sialyl-Tn O-glycan in human breast cancer

TL;DR: The development of a Chinese hamster ovary cell line expressing Muc1 and ST6GalNAc-I allowed the large scale production of MUC1 carrying 83% sialyl-Tn O-glycans, and the availability of large quantities of this MUC 1 glycoform will allow the evaluation of its efficacy as an immunogen for immunotherapy of M UC1/STn-expressing tumors.