H
Hatem M. Gaber
Researcher at Cairo University
Publications - 35
Citations - 608
Hatem M. Gaber is an academic researcher from Cairo University. The author has contributed to research in topics: Pyrazole & Reactivity (chemistry). The author has an hindex of 12, co-authored 35 publications receiving 483 citations.
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Journal ArticleDOI
The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis
TL;DR: The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed in this paper, where their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophilic, alkenes, and alkynes are discussed.
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One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents.
Abdelwahed R. Sayed,Sobhi M. Gomha,Sobhi M. Gomha,Eman A. Taher,Zeinab A. Muhammad,Hesham R. El-Seedi,Hesham R. El-Seedi,Hatem M. Gaber,Mahgoub M Ahmed +8 more
TL;DR: Thiazole scaffolds 4c, 4d and 8c showed anticancer activities in the micromolar range and are appropriate as a candidate for cancer treatment and suggested that the mechanism of the anticancer action exerted by the most active compounds inside HCT-116 cells was apoptosis through the Bcl-2 family.
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Recent developments in chemical reactivity of N,N-dimethylenamino ketones as synthons for various heterocycles
TL;DR: In this paper, the authors present recent progress in the utility of N,N-dimethyl enaminones as building blocks for a diverse range of acyclic, carbocyclic and five-and six-membered heterocyclics.
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Studies on Enaminonitriles: a New Synthesis of 1,3-Substituted Pyrazole-4-carbonitrile
TL;DR: This paper showed that 3-Diethylaminoacrylonitrile reacts with hydrazonyl halides to yield 1,3-disubstituted pyrazole-4-carbonitriles 5a-d.
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Studies with Functionally Substituted Enamines: Synthesis of New Aminoazolo-Pyrimidines and -1,2,4-Triazines:
TL;DR: 3-Aminoacrylonitrile derivatives (1d-g) coupled with aromatic and heteroaromatic diazonium salts yielding arylhydrazonals and pyrazolo[5,1-c]triazines were used in this paper.