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Ismail A. Abdelhamid

Researcher at Cairo University

Publications -  179
Citations -  2165

Ismail A. Abdelhamid is an academic researcher from Cairo University. The author has contributed to research in topics: Chemistry & Catalysis. The author has an hindex of 23, co-authored 149 publications receiving 1414 citations. Previous affiliations of Ismail A. Abdelhamid include Leibniz University of Hanover & Kuwait University.

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Synthesis, characterization and antimicrobial activity of a novel chitosan Schiff bases based on heterocyclic moieties

TL;DR: Three heteroaryl pyrazole derivatives were synthesized and reacted with chitosan to form Schiff bases of chitOSan and indicated that the antimicrobial activity was dependent on the type of the Schiff base moiety.
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Enamines as Precursors to Polyfunctional Heteroaromatic Compounds; a Decade of Development

TL;DR: In this article, the synthesis and utilization of enamines as precursors for heterocyclic and carbocycic compounds are reviewed. And two general synthetic routes for preparation of enamine based on condensation and addition reactions are discussed.
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Molecular docking simulation and anticancer assessment on human breast carcinoma cell line using novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile) and bis(1,4-dihydropyrazolo[4',3':5,6]pyrano[2,3-b]pyridine-6-carbonitrile) derivatives.

TL;DR: An efficient route for the synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile) derivatives is reported and indicated the best binding mode compared to the standard ligand sorafenib.
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Cytotoxic and antimicrobial evaluations of novel apoptotic and anti-angiogenic spiro cyclic 2-oxindole derivatives of 2-amino-tetrahydroquinolin-5-one.

TL;DR: Two novel series of cyclic 2‐oxindole derivatives incorporating 2‐amino‐tetrahydroquinolin‐5‐one and 15b showed apoptotic inhibition of the proliferation of human breast adenocarcinoma MCF‐7 cells through DNA fragmentation and the inhibition of angiogenesis by decreasing vascular endothelial growth factor expression and secretion.
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Synthesis and Anti‐influenza Virus Activity of Novel bis(4H‐chromene‐3‐carbonitrile) Derivatives

TL;DR: An efficient and convenient method for the synthesis of bis(4H-chromene-3 carbonitrile) derivatives by one-pot, multicomponent reaction of bis-aldehydes, malononitrile, and dimedone in the presence of a catalytic amount of piperidine is reported in this paper.