H
Heba A. Mohamed
Researcher at University of Leeds
Publications - 7
Citations - 360
Heba A. Mohamed is an academic researcher from University of Leeds. The author has contributed to research in topics: Carbene & Theophylline. The author has an hindex of 5, co-authored 7 publications receiving 190 citations.
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Journal ArticleDOI
Metal complexes as a promising source for new antibiotics.
Angelo Frei,Johannes Zuegg,Alysha G. Elliott,Murray V. Baker,Stefan Braese,Christopher L. Brown,Feng Chen,Christopher G. Dowson,Gilles Dujardin,Nicole Jung,A. Paden King,Ahmed M. Mansour,Massimiliano Massi,John Moat,Heba A. Mohamed,Anna K. Renfrew,Peter J. Rutledge,Peter J. Sadler,Matthew H. Todd,Matthew H. Todd,Charlotte E. Willans,Justin J. Wilson,Mark E. Cooper,Mark A. T. Blaskovich +23 more
TL;DR: Metal complexes were evaluated against dangerous ESKAPE pathogens and found to have a higher hit-rate than organic molecules.
Journal ArticleDOI
Synthesis and anticancer activity of silver(I)-N-heterocyclic carbene complexes derived from the natural xanthine products caffeine, theophylline and theobromine.
TL;DR: It appears that the steric effect of the ligand and the hydrophobicity of the complex both play a role in the chemosensitivity of these compounds, with greater steric bulk and greater hydrophilicity delivering higher cytotoxicity.
Journal ArticleDOI
Correction: Metal complexes as a promising source for new antibiotics.
Angelo Frei,Johannes Zuegg,Alysha G. Elliott,Murray V. Baker,Stefan Braese,Christopher L. Brown,Feng Chen,Christopher G. Dowson,Gilles Dujardin,Nicole Jung,A. Paden King,Ahmed M. Mansour,Massimiliano Massi,John Moat,Heba A. Mohamed,Anna K. Renfrew,Peter J. Rutledge,Peter J. Sadler,Matthew H. Todd,Matthew H. Todd,Charlotte E. Willans,Justin J. Wilson,Mark E. Cooper,Mark A. T. Blaskovich +23 more
TL;DR: Correction for ‘Metal complexes as a promising source for new antibiotics’ by Angelo Frei et al., Chem.
Book ChapterDOI
Chapter 2:Silver-N-heterocyclic carbene complexes as promising anticancer compounds
TL;DR: These initial achievements highlight the great potential of silver-N-heterocyclic carbenes as anticancer compounds, with recent studies demonstrating their effectiveness against cancer cells.
Journal ArticleDOI
Silver(I) N-Heterocyclic Carbene Complexes Derived from Clotrimazole: Antiproliferative Activity and Interaction with an Artificial Membrane-Based Biosensor
Heba A. Mohamed,Samantha L. Shepherd,Nicola William,Helen A. Blundell,Madhurima Das,Christopher M. Pask,Benjamin R. M. Lake,Roger M. Phillips,Andrew Nelson,Charlotte E. Willans +9 more
TL;DR: With the aim of combining the potential anticancer properties of both clotrimazole, an imidazole based antifungal agent, and silver(I) N-heterocyclic carbenes, 13 novel silver-N-heterocytes are developed.