H
Hedvika Novotny
Researcher at University of Basel
Publications - 11
Citations - 974
Hedvika Novotny is an academic researcher from University of Basel. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 9, co-authored 11 publications receiving 935 citations.
Papers
More filters
Journal ArticleDOI
Prognostic relevance of gene amplifications and coamplifications in breast cancer.
Khawla S. Al-Kuraya,Peter Schraml,Joachim Torhorst,Coya Tapia,Boriana M. Zaharieva,Hedvika Novotny,Hanspeter Spichtin,Robert Maurer,Martina Mirlacher,O.R. Köchli,Markus Zuber,Holger Dieterich,Friedrich Mross,Kim Wilber,Ronald Simon,Guido Sauter +15 more
TL;DR: In this article, the authors analyzed a breast cancer tissue microarray containing samples from 2197 cancers with follow-up information and found that the presence of one or several gene amplifications may have prognostic significance.
Journal ArticleDOI
HER2, TOP2A, CCND1, EGFR and C‐MYC oncogene amplification in colorectal cancer
Khawla S. Al-Kuraya,Hedvika Novotny,Prashant Bavi,Abdul K. Siraj,Shahab Uddin,Adnan Ezzat,Nasser Al Sanea,Fouad Al-Dayel,Hadeel Al-Mana,Salwa S. Sheikh,Martina Mirlacher,Coya Tapia,Ronald Simon,Guido Sauter,Luigi Terracciano,Luigi Tornillo +15 more
TL;DR: Although no molecular differences were found between incidences of colon cancer cases in Swiss and Saudi populations, these observations emphasise the urgent need for clinical studies investigating the effect of targeted therapies.
Journal ArticleDOI
HER2 gene status in primary breast cancers and matched distant metastases
Coya Tapia,Spasenija Savic,Urs Wagner,René Schönegg,Hedvika Novotny,Bruno Grilli,Michelle Herzog,Audrey Barascud,Inti Zlobec,Gieri Cathomas,Luigi Terracciano,Georg Feichter,Lukas Bubendorf +12 more
TL;DR: Her2 gene status remains highly conserved as breast cancers metastasise, however, discrepant results do occur because of interpretational difficulties and heterogeneity of HER2 amplification.
HER2 gene status in primary breast cancers and matched distant
Spasenija Savic,Urs Wagner,René Schönegg,Hedvika Novotny,Bruno Grilli,Michelle Herzog,Audrey Barascud,Inti Zlobec,Gieri Cathomas,Luigi Terracciano,Georg Feichter,Lukas Bubendorf +11 more
TL;DR: In this paper, the authors compared the HER2 status on cytological specimens of distant metastases with the result from the primary carcinomas, and explored the prevalence of and the reasons for discrepant results.
Journal ArticleDOI
Predominance of high-grade pathway in breast cancer development of Middle East women
Khawla S. Al-Kuraya,Peter Schraml,Salwa S. Sheikh,Samir S. Amr,Joachim Torhorst,Coya Tapia,Hedvika Novotny,Hanspeter Spichtin,Robert Maurer,Martina Mirlacher,Ronald Simon,Guido Sauter +11 more
TL;DR: The data suggest that a difference in genetic susceptibility and/or lifestyle between Saudi and Swiss women has a substantial and much higher than expected impact on the risk of low-grade breast cancer.