Hee Geum Lee

TL;DR: In this article, the authors found that capsaicin induced expression of heme oxygenase-1 (HO-1) in HepG2 cells and increased the activation of Akt via phosphorylation, increasing the nuclear translocation and ARE binding of Nrf2, and upregulating HO-1.

TL;DR: In this article, the authors found capsaicin induced expression of heme oxygenase-1 (HO-1) in HepG2 cells and increased the production of reactive oxygen species (ROS).

TL;DR: This study investigated H. pylori‐induced activation of STAT3 signaling in AGS human gastric cancer cells and the underlying mechanism and found the mechanism behind this activation was still not fully understood.

TL;DR: DATS ameliorates the DSS-induced mouse colitis presumably by blocking inflammatory signaling mediated by NF-κB and STAT3.

TL;DR: Overexpression of 15-PGDH has been known to protect against experimentally induced carcinogenesis and renders the cancerous or transformed cells susceptible to apoptosis by counteracting oncogenic action of PGE(2).