H
Helen E. Benson
Researcher at University of Edinburgh
Publications - 4
Citations - 1308
Helen E. Benson is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Genome-wide association study & G protein-coupled receptor. The author has an hindex of 4, co-authored 4 publications receiving 1238 citations. Previous affiliations of Helen E. Benson include University of Cambridge.
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The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
Adam J. Pawson,Joanna L. Sharman,Helen E. Benson,Elena Faccenda,Stephen P.H. Alexander,Peter Buneman,Anthony P. Davenport,John C. McGrath,John A. Peters,Christopher Southan,Michael Spedding,Wenyuan Yu,Anthony J. Harmar,Nc-Iuphar +13 more
TL;DR: The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY is a new open access resource providing pharmacological, chemical, genetic, functional and pathophysiological data on the targets of approved and experimental drugs.
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International Union of Basic and Clinical Pharmacology. LXXXVIII. G Protein-Coupled Receptor List: Recommendations for New Pairings with Cognate Ligands
Anthony P. Davenport,Stephen P.H. Alexander,Joanna L. Sharman,Adam J. Pawson,Helen E. Benson,Amy E. Monaghan,Wen Chiy Liew,Chidochangu P. Mpamhanga,Tom I. Bonner,Richard R. Neubig,Jean-Philippe Pin,Michael Spedding,Anthony J. Harmar +12 more
TL;DR: The objective is to stimulate research into confirming pairings of orphan receptors where there is currently limited information and to identify cognate ligands for the remaining GPCRs.
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IUPHAR-DB: updated database content and new features
Joanna L. Sharman,Helen E. Benson,Adam J. Pawson,Veny Lukito,Chidochangu P. Mpamhanga,Vincent Bombail,Anthony P. Davenport,John A. Peters,Michael Spedding,Anthony J. Harmar,Nc-Iuphar +10 more
TL;DR: In this update, 366 endogenous peptide ligands with their amino acid sequences, post-translational modifications, links to precursor genes, species differences and relationships with other molecules in the IUPHAR-DB are annotated.
Journal ArticleDOI
Systematic Meta-Analyses and Field Synopsis of Genetic Association Studies in Colorectal Cancer
Evropi Theodoratou,Zahra Montazeri,Steven Hawken,Genevieve CdL Allum,Jacintha Gong,Valerie Tait,Iva Kirac,Mahmood Tazari,Susan M. Farrington,Alex Demarsh,Alex Demarsh,Lina Zgaga,D C Landry,Helen E. Benson,Stephanie H. Read,Igor Rudan,Albert Tenesa,Malcolm G. Dunlop,Harry Campbell,Julian Little +19 more
TL;DR: The first comprehensive field synopsis and creation of a parallel publicly available and regularly updated database that catalogs all genetic association studies on colorectal cancer is reported, providing the context for genetic association data to be interpreted appropriately and helps inform future research direction.