H
Helle Bielefeldt-Ohmann
Researcher at University of Queensland
Publications - 258
Citations - 8536
Helle Bielefeldt-Ohmann is an academic researcher from University of Queensland. The author has contributed to research in topics: Virus & Flavivirus. The author has an hindex of 45, co-authored 231 publications receiving 7377 citations. Previous affiliations of Helle Bielefeldt-Ohmann include University of Washington & Global Virus Network.
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Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major.
TL;DR: In the present study, "susceptible" mice injected with a small number of parasites mounted a cell-mediated response and acquired resistance to a larger, normally pathogenic, challenge and may be applicable in diseases in which protection is dependent on cell- mediated immunity.
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Mitogenic activity and cytokine levels in non‐healing and healing chronic leg ulcers
TL;DR: Results suggest that healing in chronic venous leg ulcers may be impaired by inflammatory mediators rather than inhibited by a deficiency of growth factors in these chronic wounds.
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Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus
Carole R. Baskin,Helle Bielefeldt-Ohmann,Terrence M. Tumpey,Patrick J. Sabourin,James P. Long,Adolfo García-Sastre,Airn-E. Tolnay,Randy A. Albrecht,John A. Pyles,Pam H. Olson,Lauri D. Aicher,Elizabeth Rosenzweig,Kaja Murali-Krishna,Edward A. Clark,Mark S. Kotur,Jamie L. Fornek,Sean Proll,Robert E. Palermo,Carol L. K. Sabourin,Michael G. Katze +19 more
TL;DR: The H5N1 virus was exceptional for the extent of tissue damage, cytokinemia, and interference with immune regulatory mechanisms, which may help explain the extreme virulence of HPAI viruses in humans.
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A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease
Madeleine M. Fort,Afsaneh Mozaffarian,Axel G. Stöver,Jean da Silva Correia,Johnson David A,R. Thomas Crane,Richard J. Ulevitch,David H. Persing,Helle Bielefeldt-Ohmann,Peter Probst,Eric W. Jeffery,Steven P. Fling,Robert M. Hershberg +12 more
TL;DR: Treatment with CRX-526 inhibits the development of moderate-to-severe disease in two mouse models of colonic inflammation: the dextran sodium sulfate model and multidrug resistance gene 1a-deficient mice.
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Dengue viral infections; pathogenesis and epidemiology.
TL;DR: A number of theories relating to the pathogenesis of dengue haemorrhagic fever exist that have evolved from the analysis of the epidemiology of this disease, but the exact mechanisms for the disease are unknown.