H
Helmut Gadner
Researcher at Boston Children's Hospital
Publications - 491
Citations - 29830
Helmut Gadner is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Transplantation & Langerhans cell histiocytosis. The author has an hindex of 88, co-authored 491 publications receiving 28124 citations. Previous affiliations of Helmut Gadner include Medical University of Vienna & University of Erlangen-Nuremberg.
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Journal ArticleDOI
Contemporary classification of histiocytic disorders
Blaise E. Favara,Alfred C. Feller,Macro Pauli,Elaine S. Jaffe,Lawrence M. Weiss,Maurizio Aricò,Peter Bucsky,R. Maarten Egeler,Göran Elinder,Helmut Gadner,Mary V. Gresik,Jan-Inge Henter,Shinsaku Imashuku,Gritta Janka-Schaub,Ron Jaffe,Stephan Ladisch,Christian Nezelof,Jon Pritchard +17 more
TL;DR: A classification of the histiocytic disorders that primarily affect children is presented in this article, where guidelines for distinguishing the exceedingly rare malignant diseases of histiocytes from large cell lymphomas through the use of a battery of special studies are provided.
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Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation.
Jan-Inge Henter,AnnaCarin Samuelsson-Horne,Maurizio Aricò,R. Maarten Egeler,Göran Elinder,Alexandra H. Filipovich,Helmut Gadner,Shinsaku Imashuku,Diane M. Komp,Stephan Ladisch,David Webb,Gritta Janka +11 more
TL;DR: HLH-94 is very effective, allowing BMT in most patients, and survival of children with HLH has been greatly improved.
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Primary Metastatic Osteosarcoma: Presentation and Outcome of Patients Treated on Neoadjuvant Cooperative Osteosarcoma Study Group Protocols
Leo Kager,Andreas Zoubek,Ulrike Pötschger,Ulrike Kastner,Silke Flege,Beate Kempf-Bielack,Detlev Branscheid,Rainer Kotz,Mechthild Salzer-Kuntschik,Winfried Winkelmann,Gernot Jundt,Hartmut Kabisch,Peter Reichardt,Heribert Jürgens,Helmut Gadner,Stefan S. Bielack +15 more
TL;DR: The number of metastases at diagnosis and the completeness of surgical resection of all clinically detected tumor sites are of independent prognostic value in patients with proven primary metastatic osteosarcoma.
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Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group.
Martin Schrappe,Alfred Reiter,Wolf-Dieter Ludwig,Jochen Harbott,Martin Zimmermann,Wolfgang Hiddemann,Charlotte M. Niemeyer,Günter Henze,Andreas Feldges,Felix Zintl,Bernhard Kornhuber,Jörg Ritter,Karl Welte,Helmut Gadner,Hansjörg Riehm +14 more
TL;DR: The overall improvement over the results in ALL-BFM 86 (6-year EFS, 72%; P =. 001) was based on fewer recurrences among patients in the MRG with B-cell-precursor ALL, indicating an advantage of more condensed induction therapy.
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MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberration.
Inge M. Ambros,Peter F. Ambros,Sabine Strehl,Heinrich Kovar,Helmut Gadner,Mechthild Salzer-Kuntschik +5 more
TL;DR: Both ES and pPNET cells express the MIC2 gene in very high amounts, which represents a highly selective and almost unique feature of these cells, making an assignment of these tumors in one entity even more likely.