J
Jan-Inge Henter
Researcher at Karolinska University Hospital
Publications - 261
Citations - 27856
Jan-Inge Henter is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Hemophagocytic lymphohistiocytosis & Langerhans cell histiocytosis. The author has an hindex of 69, co-authored 248 publications receiving 24065 citations. Previous affiliations of Jan-Inge Henter include Shandong University & Umeå University.
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Journal ArticleDOI
HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.
Jan-Inge Henter,AnnaCarin Horne,Maurizio Aricò,R. Maarten Egeler,Alexandra H. Filipovich,Shinsaku Imashuku,Stephan Ladisch,Kenneth L. McClain,David Webb,Jacek Winiarski,Gritta Janka +10 more
TL;DR: HLH‐2004 chemo‐immunotherapy includes etoposide, dexamethasone, cyclosporine A upfront and, in selected patients, intrathecal therapy with methotrexate and corticosteroids, and subsequent hematopoietic stem cell transplantation is recommended for patients with familial disease or molecular diagnosis, and patients with severe and persistent, or reactivated, disease.
Journal ArticleDOI
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Takuya Sekine,André Perez-Potti,Olga Rivera-Ballesteros,Kristoffer Strålin,Jean Baptiste Gorin,Annika Olsson,Sian Llewellyn-Lacey,Habiba Kamal,Gordana Bogdanovic,Sandra Muschiol,David J. Wullimann,Tobias Kammann,Johanna Emgård,Tiphaine Parrot,Elin Folkesson,Olav Rooyackers,Lars Eriksson,Jan-Inge Henter,Anders Sönnerborg,Tobias Allander,Jan Albert,Morten Nielsen,Jonas Klingström,Sara Gredmark-Russ,Niklas K. Björkström,Johan K. Sandberg,David Price,Hans-Gustaf Ljunggren,Soo Aleman,Marcus Buggert +29 more
TL;DR: It is shown that SARS-CoV-2 elicits robust, broad and highly functional memory T cell responses, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19.
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Perforin Gene Defects in Familial Hemophagocytic Lymphohistiocytosis
Susan E. Stepp,Dufourcq-Lagelouse R,Françoise Le Deist,Françoise Le Deist,Sadhna Bhawan,Stéphanie Certain,Porunelloor A. Mathew,Jan-Inge Henter,Michael J. Bennett,Alain Fischer,Alain Fischer,Geneviève de Saint Basile,Vinay Kumar +12 more
TL;DR: In this paper, the coding regions of the perforin gene of eight unrelated 10q21-22-linked FHL patients revealed homozygous nonsense mutations in four patients and missense mutations in the other four patients.
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Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages.
Jean-François Emile,Oussama Abla,Sylvie Fraitag,AnnaCarin Horne,Julien Haroche,Jean Donadieu,Luis Requena-Caballero,Michael B. Jordan,Omar Abdel-Wahab,Carl E. Allen,Frédéric Charlotte,Eli L. Diamond,R. Maarten Egeler,Alain Fischer,Alain Fischer,Juana Gil Herrera,Jan-Inge Henter,Filip Janku,Miriam Merad,Jennifer Picarsic,Carlos Rodriguez-Galindo,Barret J. Rollins,Barret J. Rollins,Abdellatif Tazi,Robert Vassallo,Lawrence M. Weiss +25 more
TL;DR: This revised classification system consists of 5 groups of diseases: (1) Langerhans-related, (2) cutaneous and mucocutaneous, and (3) malignant histiocytoses as well as (4) Rosai-Dorfman disease and (5) hemophagocytic lymphohistiocyts and macrophage activation syndrome.
Journal ArticleDOI
Contemporary classification of histiocytic disorders
Blaise E. Favara,Alfred C. Feller,Macro Pauli,Elaine S. Jaffe,Lawrence M. Weiss,Maurizio Aricò,Peter Bucsky,R. Maarten Egeler,Göran Elinder,Helmut Gadner,Mary V. Gresik,Jan-Inge Henter,Shinsaku Imashuku,Gritta Janka-Schaub,Ron Jaffe,Stephan Ladisch,Christian Nezelof,Jon Pritchard +17 more
TL;DR: A classification of the histiocytic disorders that primarily affect children is presented in this article, where guidelines for distinguishing the exceedingly rare malignant diseases of histiocytes from large cell lymphomas through the use of a battery of special studies are provided.