H
Henriette Rudolph
Researcher at Boston Children's Hospital
Publications - 18
Citations - 366
Henriette Rudolph is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Choroid plexus & Medicine. The author has an hindex of 8, co-authored 15 publications receiving 243 citations. Previous affiliations of Henriette Rudolph include Heidelberg University & University of Bern.
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Journal ArticleDOI
Neuroinvasion and Inflammation in Viral Central Nervous System Infections
TL;DR: This review illustrates examples of established brain barrier models, in which the specific reaction patterns of different viral families can be analyzed, and highlights the pathogen specific array of cytokines and chemokines involved in immunological responses in viral CNS infections.
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Enterovirus Infections of the Central Nervous System in Children: An Update.
TL;DR: Improved molecular typing and several EV surveillance programs (primarily geared toward the detection of poliovirus outbreaks) have led to higher detection rates of enteroviral infections worldwide.
Journal ArticleDOI
Human CD4 + T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro
Hideaki Nishihara,Sasha Soldati,Adrien Mossu,Maria Rosito,Maria Rosito,Henriette Rudolph,William A. Muller,Daniela Latorre,Daniela Latorre,Federica Sallusto,Federica Sallusto,Mireia Sospedra,Roland Martin,Hiroshi Ishikawa,Tobias Tenenbaum,Horst Schroten,Fabien Gosselet,Britta Engelhardt +17 more
TL;DR: Analysis of the cellular and molecular mechanisms involved in the migration of different human CD4+ T-cell subsets across the BBB versus the BCSFB indicates that different Th subsets may use different anatomical routes to enter the CNS during immune surveillance versus neuroinflammation.
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Postarrest stalling rather than crawling favors CD8(+) over CD4(+) T-cell migration across the blood-brain barrier under flow in vitro.
Henriette Rudolph,Armelle Klopstein,Isabelle Gruber,Claudia Blatti,Ruth Lyck,Britta Engelhardt +5 more
TL;DR: In vitro live cell imaging directly compared the multistep extravasation of activated CD4+ and CD8+ T cells across primary mouse brain microvascular endothelial cells (pMBMECs) as a model for the blood–brain barrier (BBB) under physiological flow to establish cellular and molecular mechanisms distinguishable from those involved for CD4- T cells.
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The choroid plexus may be an underestimated site of tumor invasion to the brain: an in vitro study using neuroblastoma cell lines
Elodie Vandenhaute,Carolin Stump-Guthier,María Lasierra Losada,Tobias Tenenbaum,Henriette Rudolph,Hiroshi Ishikawa,Christian Schwerk,Horst Schroten,Matthias Dürken,Martin März,Michael Karremann +10 more
TL;DR: It is presumed that the choroid plexus might be an underestimated site of CNS invasion, since neuroblastoma cell lines are able to actively cross a choroids plexUS epithelial cell layer.