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Hermann J. Heipieper

Researcher at Helmholtz Centre for Environmental Research - UFZ

Publications -  166
Citations -  8213

Hermann J. Heipieper is an academic researcher from Helmholtz Centre for Environmental Research - UFZ. The author has contributed to research in topics: Pseudomonas putida & Biodegradation. The author has an hindex of 48, co-authored 156 publications receiving 7124 citations. Previous affiliations of Hermann J. Heipieper include University of Münster & Sapienza University of Rome.

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Mechanisms of resistance of whole cells to toxic organic solvents

TL;DR: One of the key processes in the adaptation of some Pseudomonas strains, enabling them to tolerate organic solvents appears to be the isomerization of cis - into trans-unsaturated fatty acids.
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Conversion of cis unsaturated fatty acids to trans, a possible mechanism for the protection of phenol-degrading Pseudomonas putida P8 from substrate toxicity.

TL;DR: The cis-to-trans modification of the fatty acids studied here apparently is a new way of adapting the membrane fluidity to the presence of phenols, thereby compensating for the elevation of membrane permeability induced by these toxic substances.
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Solvent-tolerant bacteria for biotransformations in two-phase fermentation systems.

TL;DR: It is anticipated that the biotechnological production of a number of important fine chemicals in amounts sufficient to compete economically with chemical syntheses will soon be possible by making use of solvent-tolerant microorganisms.
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The cis–trans isomerase of unsaturated fatty acids in Pseudomonas and Vibrio: biochemistry, molecular biology and physiological function of a unique stress adaptive mechanism

TL;DR: Evidence was obtained that isomerization does not include a transient saturation of the double bond, and such an adaptive mechanism appears to be an alternative way to regulate membrane fluidity when growth is inhibited.
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Influence of phenols on growth and membrane permeability of free and immobilized Escherichia coli.

TL;DR: The data point to the membrane as an important cell component in the toxicity of these pollutants as well as the protection of immobilized microorganisms from phenolic solvents.