H
Herold Oluoch
Researcher at Yerkes National Primate Research Center
Publications - 4
Citations - 1412
Herold Oluoch is an academic researcher from Yerkes National Primate Research Center. The author has contributed to research in topics: Immune system & Chemokine. The author has an hindex of 3, co-authored 4 publications receiving 1287 citations.
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Journal ArticleDOI
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
Troy D. Querec,Rama Akondy,Eva K. Lee,Weiping Cao,Helder I. Nakaya,Dirk E. Teuwen,Ali A. Pirani,Kim M. Gernert,Jiusheng Deng,Bruz Marzolf,Kathleen A. Kennedy,Haiyan Wu,Soumaya Bennouna,Herold Oluoch,Joseph I. Miller,Ricardo Z. N. Vêncio,Mark J. Mulligan,Alan Aderem,Rafi Ahmed,Bali Pulendran,Bali Pulendran +20 more
TL;DR: This article used a system biology approach to identify early gene signatures that predicted immune responses in humans vaccinated with the yellow fever vaccine YF-17D, with up to 90% accuracy in an independent, blinded trial.
Journal ArticleDOI
Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity.
Santhakumar Manicassamy,Rajesh Ravindran,Jiusheng Deng,Herold Oluoch,Timothy L. Denning,Sudhir Pai Kasturi,Kristen M. Rosenthal,Brian D. Evavold,Bali Pulendran,Bali Pulendran +9 more
TL;DR: A new mechanism for the systemic induction of retinoic acid and immune suppression against autoimmunity is defined, defined as Toll-like receptor 2 (TLR2) and dectin-1, recognizing the same microbial stimulus.
Journal ArticleDOI
Distinct TLR adjuvants differentially stimulate systemic and local innate immune responses in nonhuman primates
TL;DR: Different TLR-Ls mediate distinct signatures of early innate responses both locally and systemically in rhesus macaques, consistent with the effects in blood.