H
Hideki Agata
Researcher at University of Tokyo
Publications - 26
Citations - 784
Hideki Agata is an academic researcher from University of Tokyo. The author has contributed to research in topics: Stromal cell & Bone marrow. The author has an hindex of 13, co-authored 25 publications receiving 718 citations. Previous affiliations of Hideki Agata include Nagoya University & Nagasaki University.
Papers
More filters
Journal ArticleDOI
Effective Bone Engineering with Periosteum-derived Cells
Hideki Agata,Izumi Asahina,Yasuharu Yamazaki,M. Uchida,Y. Shinohara,Masaki J. Honda,Hideaki Kagami,Minoru Ueda +7 more
TL;DR: Combined treatment with bFGF and BMP-2 can make periosteum a highly useful source of bone regeneration, and compared the osteogenic potential of these cells to that of bone marrow stromal cells.
Journal ArticleDOI
Morphology-based prediction of osteogenic differentiation potential of human mesenchymal stem cells.
Fumiko Matsuoka,Ichiro Takeuchi,Hideki Agata,Hideaki Kagami,Hideaki Kagami,Hirofumi Shiono,Yasujiro Kiyota,Hiroyuki Honda,Ryuji Kato +8 more
TL;DR: The results provide strong evidence for the feasibility of using a quantitative time series of phase-contrast cellular morphology for non-invasive cell quality prediction in regenerative medicine.
Journal ArticleDOI
Bone marrow stromal cells (bone marrow-derived multipotent mesenchymal stromal cells) for bone tissue engineering: basic science to clinical translation.
TL;DR: The nature of the cells, suitable culture conditions for bone tissue engineering, and their potential therapeutic applications are reviewed with possible caveats and recent advances in bone marrow stromal cell biology are discussed with reference to clinical translation.
Journal ArticleDOI
Feasibility and efficacy of bone tissue engineering using human bone marrow stromal cells cultivated in serum-free conditions
Hideki Agata,Nobukazu Watanabe,Yumiko Ishii,Noriyuki Kubo,Satoshi Ohshima,Mika Yamazaki,Arinobu Tojo,Hideaki Kagami +7 more
TL;DR: The feasibility and efficacy of bone tissue engineering with human bone marrow stromal cells (BMSCs) expanded in serum-free conditions is reported and as efficient as that obtained with BMSCs expanded in conventional serum-containing medium.
Journal ArticleDOI
Characteristic change and loss of in vivo osteogenic abilities of human bone marrow stromal cells during passage.
Hideki Agata,Izumi Asahina,Nobukazu Watanabe,Yumiko Ishii,Noriyuki Kubo,Satoshi Ohshima,Mika Yamazaki,Arinobu Tojo,Hideaki Kagami +8 more
TL;DR: There are several required conditions for human BMSCs to demonstrate their bone-forming capabilities, which should be further investigated and considered when designing a protocol for clinical bone tissue engineering.