H
Hideki Hirakawa
Researcher at Kyushu University
Publications - 24
Citations - 3481
Hideki Hirakawa is an academic researcher from Kyushu University. The author has contributed to research in topics: Genome & Whole genome sequencing. The author has an hindex of 14, co-authored 24 publications receiving 3187 citations.
Papers
More filters
Journal ArticleDOI
Mining of the Uncharacterized Cytochrome P450 Genes Involved in Alkaloid Biosynthesis in California Poppy Using a Draft Genome Sequence
Kentaro Hori,Yasuyuki Yamada,Ratmoyo Purwanto,Yohei Minakuchi,Atsushi Toyoda,Hideki Hirakawa,Fumihiko Sato +6 more
TL;DR: Describing the P450 genes involved in benzylisoquinoline alkaloid biosynthesis in California poppy revealed two highly homologous P450s (CYP82P2 and CYP82P3) that exhibited 10-hydroxylase activities with different substrate specificities.
Journal ArticleDOI
Comparison of Outer Membrane Protein Genes omp and pmp in the Whole Genome Sequences of Chlamydia pneumoniae Isolates from Japan and the United States
Mutsunori Shirai,Hideki Hirakawa,Kazunobu Ouchi,Mitsuaki Tabuchi,Fumio Kishi,Mitsuaki Kimoto,Hiroaki Takeuchi,Junko Nishida,Kaori Shibata,Ryutaro Fujinaga,Hiroshi Yoneda,Hiroshi Matsushima,Chiho Tanaka,Susumu Furukawa,Koshiro Miura,Atsushi Nakazawa,Kazuo Ishii,Tadayoshi Shiba,Masahira Hattori,Satoru Kuhara,Teruko Nakazawa +20 more
TL;DR: A comparative study of the OMPs of the two strains revealed a nucleotide sequence identity of 89.6%-100% (deduced amino acid sequence identity, 71.1%-100%) that may be essential for specific attributes that define the differential biology of two C. pneumoniae strains.
Journal ArticleDOI
Insights into the evolution of symbiosis gene copy number and distribution from a chromosome-scale Lotus japonicus Gifu genome sequence.
Nadia Kamal,Terry Mun,Dugald Reid,Jie Shun Lin,Turgut Yigit Akyol,Niels Sandal,Torben Asp,Hideki Hirakawa,Jens Stougaard,Klaus F. X. Mayer,Shusei Sato,Stig U. Andersen +11 more
TL;DR: It is shown that the symbiotic islands recently described in Medicago truncatula do not appear to be conserved in L. japonicus, providing a first example of a high-quality chromosome-scale reference genome assembly for the herbaceous perennial legume.
Journal ArticleDOI
Comparative DNA sequence analysis of mouse and human CC chemokine gene clusters.
Hisayuki Nomiyama,Kimie Egami,Sumio Tanase,Retsu Miura,Hideki Hirakawa,Satoru Kuhara,Jun Ogasawara,Shinichi Morishita,Osamu Yoshie,Jun Kusuda,Katsuyuki Hashimoto +10 more
TL;DR: Comparison of the genomic sequences unambiguously identified the orthologous relationships of some of the chemokine genes in the mouse and human CC gene clusters, and revealed that numerous gene rearrangements have occurred even after the diversification of rodents and primates, resulting in several species-specific chemokines.
Journal ArticleDOI
Amino Acid Residue Substitution at T-Cell Determinant-flanking Sites in β-Lactoglobulin Modulates Antigen Presentation to T Cells through Subtle Conformational Change
Akio Ametani,Akio Ametani,Toshio Sakurai,Yoshinori Katakura,Yoshinori Katakura,Satoru Kuhara,Hideki Hirakawa,Tomohiro Hosoi,Shun Ichi Dosako,Shuichi Kaminogawa,Shuichi Kaminogawa +10 more
TL;DR: Substitution of two amino acid residues at sites distant from the T-cell determinant induced differential determinant display on antigen-presenting cells, possibly due to subtle conformational changes in β-LG.