H
Hideya Sakaguchi
Researcher at Kumamoto University
Publications - 13
Citations - 366
Hideya Sakaguchi is an academic researcher from Kumamoto University. The author has contributed to research in topics: Cerebral amyloid angiopathy & Amyloid. The author has an hindex of 7, co-authored 13 publications receiving 295 citations.
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Journal ArticleDOI
Anti-amyloid β autoantibodies in cerebral amyloid angiopathy-related inflammation: implications for amyloid-modifying therapies.
Fabrizio Piazza,Steven M. Greenberg,Mario Savoiardo,Margherita Gardinetti,Luisa Chiapparini,Irina Raicher,Ricardo Nitrini,Hideya Sakaguchi,M. Brioschi,Giuseppe Billo,Antonio Colombo,Francesca Lanzani,Giuseppe Piscosquito,Maria Rita Carriero,Giorgio Giaccone,Fabrizio Tagliavini,Carlo Ferrarese,Jacopo C. DiFrancesco +17 more
TL;DR: The role of anti–amyloid β (Aβ) autoantibodies in the acute and remission phases of cerebral amyloid angiopathy–related inflammation is investigated.
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Cerebral amyloid angiopathy-related inflammation presenting with steroid-responsive higher brain dysfunction: case report and review of the literature
Hideya Sakaguchi,Akihiko Ueda,Takayuki Kosaka,Satoshi Yamashita,En Kimura,Taro Yamashita,Yasushi Maeda,Teruyuki Hirano,Makoto Uchino +8 more
TL;DR: Pulse steroid therapy was so effective that clinical and radiological findings immediately improved and cerebral biopsy with histological confirmation remains necessary for an accurate diagnosis of cerebral amyloid angiopathy (CAA)-related inflammation.
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Sporadic juvenile amyotrophic lateral sclerosis caused by mutant FUS/TLS: possible association of mental retardation with this mutation
Satoshi Yamashita,Akira Mori,Hideya Sakaguchi,Tomohiro Suga,Daijirou Ishihara,Akihiko Ueda,Taro Yamashita,Yasushi Maeda,Makoto Uchino,Teruyuki Hirano +9 more
TL;DR: Molecular analysis revealed that the mutant FUS/TLS, especially the deletion/frameshift mutation, showed significant cytoplasmic localization in transfected motor neuron-like cells, and suggest the association of mental retardation with the FUS-TLS mutation.
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Optineurin is potentially associated with TDP-43 and involved in the pathogenesis of inclusion body myositis
Satoshi Yamashita,En Kimura,N. Tawara,Hideya Sakaguchi,Tatsuya Nakama,Yasushi Maeda,Teruyuki Hirano,Makoto Uchino,Yukio Ando +8 more
TL;DR: A comparison study of thenaecology and Applied Neurobiology in patients with and without Alzheimer's disease shows clear trends in prognosis and in particular in the cases of patients with a history of abuse.
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A novel GJB1 frameshift mutation produces a transient CNS symptom of X-linked Charcot–Marie–Tooth disease
Hideya Sakaguchi,Satoshi Yamashita,Akiko Miura,Tomoo Hirahara,En Kimura,Yasushi Maeda,Tadashi Terasaki,Teruyuki Hirano,Makoto Uchino +8 more
TL;DR: The first case with a novel GJB1 frameshift mutation that associates with a transient central nervous system symptoms with abnormal brain magnetic resonance imaging (MRI) is reported, which indicates inflammation might be involved in the pathophysiology of CMT1X with the GJB 1 mutation.