L
Luisa Chiapparini
Researcher at Carlo Besta Neurological Institute
Publications - 160
Citations - 4255
Luisa Chiapparini is an academic researcher from Carlo Besta Neurological Institute. The author has contributed to research in topics: Medicine & Magnetic resonance imaging. The author has an hindex of 33, co-authored 143 publications receiving 3516 citations. Previous affiliations of Luisa Chiapparini include Belfast City Hospital & University of Southern Denmark.
Papers
More filters
Journal ArticleDOI
Age-related iron deposition in the basal ganglia: Quantitative analysis in healthy subjects
Domenico Aquino,Alberto Bizzi,Marina Grisoli,Barbara Garavaglia,Maria Grazia Bruzzone,Nardo Nardocci,Mario Savoiardo,Luisa Chiapparini +7 more
TL;DR: R2* measurements can be used to quantify brain iron accumulation and thus may allow better evaluation of neurodegenerative diseases associated with iron deposition, as well as compare with previously reported iron concentrations found in autopsy material.
Journal ArticleDOI
Anti-amyloid β autoantibodies in cerebral amyloid angiopathy-related inflammation: implications for amyloid-modifying therapies.
Fabrizio Piazza,Steven M. Greenberg,Mario Savoiardo,Margherita Gardinetti,Luisa Chiapparini,Irina Raicher,Ricardo Nitrini,Hideya Sakaguchi,M. Brioschi,Giuseppe Billo,Antonio Colombo,Francesca Lanzani,Giuseppe Piscosquito,Maria Rita Carriero,Giorgio Giaccone,Fabrizio Tagliavini,Carlo Ferrarese,Jacopo C. DiFrancesco +17 more
TL;DR: The role of anti–amyloid β (Aβ) autoantibodies in the acute and remission phases of cerebral amyloid angiopathy–related inflammation is investigated.
Journal ArticleDOI
Exome Sequence Reveals Mutations in CoA Synthase as a Cause of Neurodegeneration with Brain Iron Accumulation
Sabrina Dusi,Lorella Valletta,Tobias B. Haack,Yugo Tsuchiya,Paola Venco,Sebastiano Pasqualato,Paola Goffrini,Marco Tigano,Nikita Demchenko,Thomas Wieland,Thomas Schwarzmayr,Tim M. Strom,Federica Invernizzi,Barbara Garavaglia,Allison Gregory,Lynn Sanford,Jeffrey Hamada,Conceição Bettencourt,Henry Houlden,Luisa Chiapparini,Giovanna Zorzi,Manju A. Kurian,Manju A. Kurian,Nardo Nardocci,Holger Prokisch,Susan J. Hayflick,Ivan Gout,Valeria Tiranti +27 more
TL;DR: Changes in RNA and protein expression levels of CoA synthase, as well as CoA amount, are demonstrated in fibroblasts derived from the two clinical cases and in yeast, demonstrating the second inborn error of coenzyme A biosynthesis to be implicated in NBIA.
Journal ArticleDOI
Stimulation of the globus pallidus internus for childhood-onset dystonia.
Giovanna Zorzi,Carlo Efisio Marras,Nardo Nardocci,Angelo Franzini,Luisa Chiapparini,Elio Maccagnano,L. Angelini,Dario Caldiroli,Giovanni Broggi +8 more
TL;DR: DBS of the globus pallidus internus of the GPi was effective in 12 patients with childhood‐onset generalized dystonia refractory to medication, including 3 patients with status dystonicus, and it is suggested that it should be considered the treatment of choice for these conditions.
Journal ArticleDOI
Overlapping phenotypes in complex spastic paraplegias SPG11, SPG15, SPG35 and SPG48
Viviana Pensato,Barbara Castellotti,Cinzia Gellera,Davide Pareyson,Claudia Ciano,Lorenzo Nanetti,Ettore Salsano,Giuseppe Piscosquito,Elisa Sarto,Marica Eoli,Isabella Moroni,Paola Soliveri,Elena Lamperti,Luisa Chiapparini,Daniela Di Bella,Franco Taroni,Caterina Mariotti +16 more
TL;DR: The observation of common clinical features in association with defects in different causative genes, suggest a general vulnerability of the corticospinal tract axons to a wide spectrum of cellular alterations.