Hila Sberro

TL;DR: This work has identified a previously unknown temporal expression program and expression hierarchy that matches the enzyme order in unbranched pathways of Escherichia coli and suggests that metabolic regulation networks are designed to generate precision promoter timing and activity programs that can be understood using the engineering principles of production pipelines.

TL;DR: A six‐gene cassette in Bacillus cereus which, when integrated into the Bacillus subtilis genome, confers resistance to a broad range of phages, including both virulent and temperate ones, and suggests that methylation on non‐palindromic TAGGAG motifs in the bacterial genome guides self/non‐self discrimination and is essential for the defensive function of the BREX system.

TL;DR: It is shown that decoding the pre-steady-state morphogen profile can reduce patterning errors caused by fluctuations in the rate of morphogen production, which can explain the surprisingly small shifts in gap and pair-rule gene expression domains observed in response to alterations in bcd dosage.

TL;DR: The results suggest that DISARM is a new type of multi-gene restriction–modification module, expanding the arsenal of defence systems known to be at the disposal of prokaryotes against their viruses.

TL;DR: The Metagenomic Gut Virus catalogue as discussed by the authors contains 189,680 genomes from 11,810 publicly available human stool metagenomes and identified 54,118 candidate viral species, 92% of which were not found in existing databases.