H
Himanshu Kumar
Researcher at Indian Institute of Science
Publications - 127
Citations - 11986
Himanshu Kumar is an academic researcher from Indian Institute of Science. The author has contributed to research in topics: Innate immune system & Immune system. The author has an hindex of 32, co-authored 97 publications receiving 10353 citations. Previous affiliations of Himanshu Kumar include Osaka University & Indian Institute of Science Education and Research, Bhopal.
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Sentinels of innate immunity in disease pathogenesis and development of therapeutics.
TL;DR: Host immunity ensures protection against a foreign intrusion having the potential to disrupt the physiological balances of the host as discussed by the authors, which is a first line of defense and is instrumental in defending against intrusions.
Journal ArticleDOI
In This Issue: Protein Structure, Cellular Metabolism, and Genetics in Immunity.
Himanshu Kumar,Adrian Bot +1 more
TL;DR: The quality and magnitude of host immune responses do not rely on the genetic background alone, but also depend on several cis- and trans-regulatory factors, epigenetic modifications of genomic DNA...
Posted ContentDOI
Integrated role of microRNA-30e-5p through targeting negative regulators of innate immune pathways during HBV infection and SLE
Richa Mishra,Sanjana Bhattacharya,Bhupendra Singh Rawat,Ashish Kumar,Akhilesh Kumar,Kavita Niraj,Ajit Chande,Puneet Gandhi,Dheeraj Khetan,Amita Aggarwal,Seiichi Sato,Prafullakumar Tailor,Akinori Takaoka,Himanshu Kumar,Himanshu Kumar +14 more
TL;DR: In this article, the authors identified microRNA(miR)-30e-5p (miR-30e) induced by the hepatitis B virus (HBV) and other viruses that act as a master regulator for innate immune responses.
Posted ContentDOI
Pseudo-grading of tumor subclones using phenotype algebra
Namrata Bhattacharya,Anja Rockstroh,Sanket Deshpande,Samiwel Thomas,Smriti Chawla,Pierre Solomon,Cynthia Fourgeux,Gaurav Ahuja,Brett G. Hollier,Himanshu Kumar,Antoine Roquilly,Jeremie Poschmann,Melanie Lehman,Colleen C. Nelson,Debarka Sengupta +14 more
TL;DR: In this paper , the authors present a computational approach that facilitates risk-stratification by leveraging scRNA-seq profiles and language modeling techniques, which catalyzes the simulation of the residual phenotype following positive and negative selection of specific malignant cell subtypes in a tumor.
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Current Landscape of Therapeutics for the Management of Hypertension - A Review.
TL;DR: In this article , the authors present contemporary viewpoints and novel treatment options, including cutting-edge technological applications and emerging interventional and pharmaceutical therapies, as well as key concerns arising from several years of research and epidemiological observations related to the management of hypertension.