H
Hind Abdo
Researcher at Karolinska Institutet
Publications - 15
Citations - 2654
Hind Abdo is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Neuroprotection & Enteric nervous system. The author has an hindex of 13, co-authored 15 publications receiving 2008 citations. Previous affiliations of Hind Abdo include French Institute of Health and Medical Research & University of Nantes.
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Journal ArticleDOI
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
Dmitry Usoskin,Alessandro Furlan,Saiful Islam,Hind Abdo,Peter Lönnerberg,Daohua Lou,Jens Hjerling-Leffler,Jesper Z. Haeggström,Olga Kharchenko,Peter V. Kharchenko,Sten Linnarsson,Patrik Ernfors +11 more
TL;DR: The results suggest that itching during inflammatory skin diseases such as atopic dermatitis is linked to a distinct itch-generating type, and demonstrate single-cell RNA-seq as an effective strategy for dissecting sensory responsive cells into distinct neuronal types.
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Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla
Alessandro Furlan,Vyacheslav Dyachuk,Vyacheslav Dyachuk,Vyacheslav Dyachuk,Maria Eleni Kastriti,Laura Calvo-Enrique,Hind Abdo,Saida Hadjab,Tatiana Chontorotzea,Natalia Akkuratova,Natalia Akkuratova,Dmitry Usoskin,Dmitry Kamenev,Julian Petersen,Kazunori Sunadome,Fatima Memic,Ulrika Marklund,Kaj Fried,Piotr Topilko,Francois Lallemend,Peter V. Kharchenko,Patrik Ernfors,Igor Adameyko +22 more
TL;DR: By revisiting development of the adrenergic sympathetic system, a new cellular origin of this nervous system component is discovered, found that chromaffin cells of the Adrenal medulla are formed from peripheral glia stem cells, termed Schwann cell precursors.
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Specialized cutaneous Schwann cells initiate pain sensation
Hind Abdo,Laura Calvo-Enrique,Jose Martinez Lopez,Jianren Song,Ming-Dong Zhang,Dmitry Usoskin,Abdeljabbar El Manira,Igor Adameyko,Jens Hjerling-Leffler,Patrik Ernfors +9 more
TL;DR: A specialized cutaneous glial cell type with extensive processes forming a mesh-like network in the subepidermal border of the skin that conveys noxious thermal and mechanical sensitivity is discovered.
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miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes.
Changgeng Peng,Lili Li,Ming-Dong Zhang,Carolina Bengtsson Gonzales,Marc Parisien,Inna Belfer,Dmitry Usoskin,Hind Abdo,Alessandro Furlan,Martin Häring,Francois Lallemend,Tibor Harkany,Tibor Harkany,Luda Diatchenko,Tomas Hökfelt,Jens Hjerling-Leffler,Patrik Ernfors +16 more
TL;DR: Both basal mechanical and neuropathic pain are controlled by the microRNA-183 (miR-183) cluster in mice, and a single microRNA cluster continuously scales acute noxious mechanical sensitivity in nociceptive neurons and suppresses neuropathicPain transduction in a specific, light-touch–sensitive neuronal type recruited during mechanical allodynia.
Journal ArticleDOI
Enteric glial cells protect neurons from oxidative stress in part via reduced glutathione
Hind Abdo,Pascal Derkinderen,Priya Martina Gomes,Julien Chevalier,Julien Chevalier,Philippe Aubert,Philippe Aubert,Damien Masson,Damien Masson,Jean-Paul Galmiche,Jean-Paul Galmiche,Pieter Vanden Berghe,Michel Neunlist,Bernard Lardeux,Bernard Lardeux +14 more
TL;DR: The neuroprotective effects of EGCs were identified via their release of reduced glutathione, extending their critical role in physiological contexts and in enteric neuropathies.