H
Hiroshi Fujii
Researcher at Shinshu University
Publications - 148
Citations - 3964
Hiroshi Fujii is an academic researcher from Shinshu University. The author has contributed to research in topics: Medicine & Fatty acid-binding protein. The author has an hindex of 33, co-authored 120 publications receiving 3560 citations. Previous affiliations of Hiroshi Fujii include University of Fukui & Niigata University.
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Journal ArticleDOI
Identification of a Bile Acid-responsive Element in the Human Ileal Bile Acid-binding Protein Gene INVOLVEMENT OF THE FARNESOID X RECEPTOR/9-cis-RETINOIC ACID RECEPTOR HETERODIMER
Jacques Grober,Isabelle Zaghini,Hiroshi Fujii,Stacey A. Jones,Steven A. Kliewer,Timothy M. Willson,Teruo Ono,Philippe Besnard +7 more
TL;DR: FXR is a physiological BA sensor that is likely to play an essential role in BA homeostasis through the regulation of genes involved in their enterohepatic circulation.
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Constitutive Regulation of Cardiac Fatty Acid Metabolism through Peroxisome Proliferator-activated Receptor α Associated with Age-dependent Cardiac Toxicity
Kenichi Watanabe,Hiroshi Fujii,Toshihiro Takahashi,Makoto Kodama,Yoshifusa Aizawa,Yoshimi Ohta,Teruo Ono,Go Hasegawa,Makoto Naito,Tamie Nakajima,Yuji Kamijo,Frank J. Gonzalez,Toshifumi Aoyama +12 more
TL;DR: The results presented here indicate that PPARα controls constitutive fatty acid oxidation, thus establishing a role for the receptor in cardiac fatty acid homeostasis and altered expression of fatty acid-metabolizing proteins seems to lead to myocardial damage and fibrosis.
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Intestinal fatty acid-binding protein is a useful diagnostic marker for mesenteric infarction in humans
Tatsuo Kanda,Hiroshi Fujii,Tatsuo Tani,Hiroshi Murakami,Takeyasu Suda,Yasuo Sakai,Teruo Ono,Katsuyoshi Hatakeyama +7 more
TL;DR: I-FABP is a useful biochemical marker for the accurate diagnosis of mesenteric infarction and is evaluated as a human homologue for the diagnosis of acute ischemic diseases of the bowel.
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Urinary Excretion of Fatty Acid-Binding Protein Reflects Stress Overload on the Proximal Tubules
Atsuko Kamijo,Takeshi Sugaya,Akihisa Hikawa,Mitsuhiro Okada,Fumikazu Okumura,Masaya Yamanouchi,Akiko Honda,Masaru Okabe,Tomoya Fujino,Yasunobu Hirata,Masao Omata,Ritsuko Kaneko,Hiroshi Fujii,Akiyoshi Fukamizu,Kenjiro Kimura +14 more
TL;DR: The experimental model suggests that urinary excretion of hL-FABP reflects stresses, such as urinary protein overload, on the proximal tubules, and the clinical observations support this hypothesis.