H
Hiroshi Moro
Researcher at Niigata University
Publications - 35
Citations - 569
Hiroshi Moro is an academic researcher from Niigata University. The author has contributed to research in topics: Pneumonia & Interleukin 21. The author has an hindex of 10, co-authored 32 publications receiving 422 citations. Previous affiliations of Hiroshi Moro include University of California, San Diego.
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Journal ArticleDOI
Clinicopathologic analysis of TAFRO syndrome demonstrates a distinct subtype of HHV-8-negative multicentric Castleman disease
Noriko Iwaki,David C. Fajgenbaum,Christopher S. Nabel,Yuka Gion,Eisei Kondo,Mitsuhiro Kawano,Taro Masunari,Isao Yoshida,Hiroshi Moro,Koji Nikkuni,Kazue Takai,Kosei Matsue,Mitsutoshi Kurosawa,Masao Hagihara,Akio Saito,Masataka Okamoto,Kenji Yokota,Shinichiro Hiraiwa,Naoya Nakamura,Shinji Nakao,Tadashi Yoshino,Yasuharu Sato +21 more
TL;DR: TAFRO syndrome is a unique subtype of iMCD that demonstrates characteristic clinicopathological findings and further study to clarify prognosis, pathophysiology, and appropriate treatment is needed.
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Clinical Significance of Interferon-γ Neutralizing Autoantibodies Against Disseminated Nontuberculous Mycobacterial Disease.
Ami Aoki,Takuro Sakagami,Kazutaka Yoshizawa,Kenjiro Shima,Mio Toyama,Yoshinari Tanabe,Hiroshi Moro,Nobumasa Aoki,Satoshi Watanabe,Toshiyuki Koya,Takashi Hasegawa,Kozo Morimoto,Atsuyuki Kurashima,Yoshihiko Hoshino,Bruce C. Trapnell,Toshiaki Kikuchi +15 more
TL;DR: Interferon-γ neutralizing autoantibodies were present in most patients with disseminated NTM infection without a diagnosis of clinical immunodeficiency and can be improved by measuring serum nIFNγ-autoAb titer.
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Prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: A systematic review with meta-analysis.
Kosaku Komiya,Bruce K. Rubin,Jun-ichi Kadota,Hiroshi Mukae,Tomohiro Akaba,Hiroshi Moro,Nobumasa Aoki,Hiroki Tsukada,Shingo Noguchi,Nobuaki Shime,Osamu Takahashi,Shigeru Kohno +11 more
TL;DR: In conclusion, aspiration pneumonia was associated with both higher in-hospital and 30-day mortality in patients with CAP outside ICU settings and with decreased ICU mortality.
Journal ArticleDOI
Elevated serum interferon γ-induced protein 10 kDa is associated with TAFRO syndrome
Noriko Iwaki,Noriko Iwaki,Yuka Gion,Eisei Kondo,Mitsuhiro Kawano,Taro Masunari,Hiroshi Moro,Koji Nikkuni,Kazue Takai,Masao Hagihara,Yuko Hashimoto,Kenji Yokota,Masataka Okamoto,Shinji Nakao,Tadashi Yoshino,Yasuharu Sato,Yasuharu Sato +16 more
TL;DR: There was a strong correlation between high serum IP- 10 and the presence of TAFRO-iMCD, suggesting that IP-10 might be involved in the pathogenesis of T AFRO- iMCD.
Journal ArticleDOI
Novel assay to detect increased level of neutralizing anti-interferon gamma autoantibodies in non-tuberculous mycobacterial patients.
Kenjiro Shima,Takuro Sakagami,Yoshinari Tanabe,Nobumasa Aoki,Hiroshi Moro,Toshiyuki Koya,Hiroshi Kagamu,Takashi Hasegawa,Eiichi Suzuki,Ichiei Narita +9 more
TL;DR: The measurement of STAT1 phosphorylation index in whole blood leukocytes and antigen capture assay are simple and useful method for detection of anti-IFN-γ neutralizing autoantibodies, and is valuable in the pathophysiological diagnosis of disseminated NTM patients without obvious immunodeficiency.