Hiroshi Wada

TL;DR: Extensive networks of HDCI fibers of various densities were found in many areas of the brain; they were particularly dense in the hypothalamus but were also found in the following areas: rostrally in the cerebral cortex, olfactory nuclei, medial amygdaloid nucleus, n.

TL;DR: A good linear correlation was obtained between values for the histamine contents of mouse brain tissues determined by this method and by a radioenzymatic method with a purified histamine-N-methyltransferase preparation.

TL;DR: Consistent with its wide-ranging output, the histaminergic neuron system regulates various activities of the brain, such as the arousal state, brain energy metabolism, locomotor activity, neuroendocrine, autonomic and vestibular functions, feeding, drinking, sexual behavior, and analgesia.

TL;DR: Plasma microRNA-21 level is a promising biochemical marker for hepatocellular carcinoma, superior to α-fetoprotein and improved for the combination of micro RNA-21 and α- Fetoprotein.

TL;DR: The molecular nature of the H1 receptor is disclosed--a receptor that mediates diverse neuronal and peripheral actions of histamine and that may be of therapeutic importance in allergy.