Holly L. Holt

TL;DR: In this paper, the authors developed a Markov, state-transition, computer simulation model and populated it with Medicare claims data and cost and outcomes data from national and multinational sources.

TL;DR: The model findings suggested that reversing obesity prevalence to levels seen 10 years ago would avert 178,071 cases of coronary heart disease, 889,872 cases of diabetes, and 111,206 total knee replacements, with black and Hispanic women experiencing disproportionate losses.

TL;DR: Honey bee genomic responses to immunostimulation are substantially broader than the previously identified canonical immune response pathways, and may mediate the behavioral changes associated with social immunity by orchestrating changes in chemical signaling.

TL;DR: This article performed a meta-analysis of multiple published and new transcriptomes using a newly developed bioinformatics approach that filters genes based on their expression profile across datasets, identifying common and unique molecular responses of a model host species, the honey bee (Apis mellifera), to its major pathogens and parasites.

TL;DR: Gene expression patterns are characterized in adult worker honey bee midgut and fat body tissue in response to Nosema infection to help disentangle the direct and indirect effects of chronic infection, and understand the molecular pathways that regulate disease symptoms.